Journal ArticleDOI
Folic acid-modified dendrimer-entrapped gold nanoparticles as nanoprobes for targeted CT imaging of human lung adencarcinoma.
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The developed Au DENPs-FA have a great potential to be used as imaging probes for targeted CT imaging of human lung adencarcinoma, indicating their good biocompatibility at the given concentration range.About:
This article is published in Biomaterials.The article was published on 2013-01-01. It has received 199 citations till now. The article focuses on the topics: Cell morphology.read more
Citations
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Gold Nanomaterials at Work in Biomedicine
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Cancer active targeting by nanoparticles: a comprehensive review of literature
TL;DR: A comprehensive review of literatures focusing on the active targeting of nanoparticles to cancer cells, including antibody and antibody fragment-based targeting, antigen-basedtargeting, aptamer- based targeting, as well as ligand-based aiming, are presented.
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Unique Roles of Gold Nanoparticles in Drug Delivery, Targeting and Imaging Applications.
TL;DR: Some recent advances in the use of Au NPs as drug carriers for the intracellular delivery of therapeutics and as molecular nanoprobes for the detection and monitoring of target molecules are focused on.
Book
Molecular Imaging
TL;DR: How imaging can be used, at least experimentally, to assess specific molecular targets will allow earlier detection and characterization of disease, earlier and direct molecular assessment of treatment effects, and a more fundamental understanding of the disease process.
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Hyaluronic acid-modified Fe3O4@Au core/shell nanostars for multimodal imaging and photothermal therapy of tumors
TL;DR: This study demonstrates a unique multifunctional theranostic nanoplatform for multi-mode imaging and photothermal therapy of tumors, which may find applications in theranostics of different types of cancer.
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Gold nanoparticles in nanomedicine: preparations, imaging, diagnostics, therapies and toxicity
Elodie Boisselier,Didier Astruc +1 more
TL;DR: This critical review provides an overall survey of the basic concepts and up-to-date literature results concerning the very promising use of gold nanoparticles (AuNPs) for medicinal applications.
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Gold Nanoparticles Are Taken Up by Human Cells but Do Not Cause Acute Cytotoxicity
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Biocompatibility of gold nanoparticles and their endocytotic fate inside the cellular compartment: a microscopic overview.
TL;DR: The findings suggest that Au(0) nanoparticles are not cytotoxic, reduce the production of reactive oxygen and nitrite species, and do not elicit secretion of proinflammatory cytokines TNF-alpha and IL1-beta, making them suitable candidates for nanomedicine.
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Active targeting schemes for nanoparticle systems in cancer therapeutics.
TL;DR: The targeting schemes explored for many of the reported nanoparticle systems suggest the great potential of targeted delivery to revolutionize cancer treatment.
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Gold nanoparticles: a new X-ray contrast agent
TL;DR: Gold nanoparticles can be used as X-ray contrast agents with properties that overcome some significant limitations of iodine-based agents, and this report is the first demonstration that gold nanoparticles may overcome these limitations.