Journal ArticleDOI
Genotoxic effects of Bismuth (III) oxide nanoparticles by Allium and Comet assay.
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TLDR
Results indicate that BONPs exhibit genotoxic activity in A. cepa root meristematic cells.About:
This article is published in Chemosphere.The article was published on 2013-09-01. It has received 57 citations till now. The article focuses on the topics: Comet assay & Chromosome aberration.read more
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Interactions between nanoparticles and plants: phytotoxicity and defense mechanisms
Jie Yang,Weidong Cao,Yukui Rui +2 more
TL;DR: This review puts forward the prospects of research direction of the environmental behavior and the biological toxicity of NPs, hoping to bring new ideas to the further research on NP phytotoxicity.
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Cationic Substitutions in Hydroxyapatite: Current Status of the Derived Biofunctional Effects and Their In Vitro Interrogation Methods.
Teddy Tite,Adrian-Claudiu Popa,Liliana Marinela Balescu,Iuliana Maria Bogdan,Iuliana Pasuk,José M.F. Ferreira,George E. Stan +6 more
TL;DR: A comprehensive inventory of the progresses achieved so far is gathered, to allow fellow researchers to compare with ease and filter the best solutions for the cation substitution of HA-based materials and enable the development of multi-functional biomedical designs.
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Genotoxicity of metal oxide nanomaterials: review of recent data and discussion of possible mechanisms
Nazanin Golbamaki,Bakhtiyor Rasulev,Bakhtiyor Rasulev,Antonio Cassano,Richard L. Marchese Robinson,Emilio Benfenati,Jerzy Leszczynski,Mark T. D. Cronin +7 more
TL;DR: This review concluded that in the majority of the publications analysed in this review, the metal oxide (or silica) nanoparticles of the same core chemical composition did not show different genotoxicity study calls in the same test, although some results are inconsistent and need to be confirmed by additional experiments.
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Lessons learned: Are engineered nanomaterials toxic to terrestrial plants?
P. Venkata Laxma Reddy,Jose A. Hernandez-Viezcas,Jose R. Peralta-Videa,Jorge L. Gardea-Torresdey +3 more
TL;DR: After scrutinizing the most recent literature, it seems that the divergence in the research results may be possibly attributed to multiple factors such as ENM properties, plant species, soil dynamics, and soil microbial community.
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Mitochondrial and Chromosomal Damage Induced by Oxidative Stress in Zn 2+ Ions, ZnO-Bulk and ZnO-NPs treated Allium cepa roots
Bilal Ahmed,Sourabh Dwivedi,Malik Zainul Abdin,Ameer Azam,Majed Al-Shaeri,Mohammad Saghir Khan,Quaiser Saquib,Abdulaziz A. Al-Khedhairy,Javed Musarrat,Javed Musarrat +9 more
TL;DR: The results elucidated A. cepa, as a good model for assessment of cytotoxicity and oxidative DNA damage with ZnO-NPs and Zn2+ in plants, as well as dose-dependent increase in ROS production and alterations in ΔΨm were observed in treated roots.
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A simple technique for quantitation of low levels of DNA damage in individual cells
TL;DR: Human lymphocytes were exposed to X-irradiation or treated with H2O2 and the extent of DNA migration was measured using a single-cell microgel electrophoresis technique under alkaline conditions and this technique appears to be sensitive and useful for detecting damage and repair in single cells.
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Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing.
Raymond R. Tice,E. Agurell,Diana Anderson,B. Burlinson,Andreas Hartmann,H. Kobayashi,Y. Miyamae,Emilio Rojas,J.-C. Ryu,Y. F. Sasaki +9 more
TL;DR: The expert panel reached a consensus that the optimal version of the Comet assay for identifying agents with genotoxic activity was the alkaline (pH > 13) versions of the assay developed by Singh et al.
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8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions.
TL;DR: These assays illustrate mutagenic replication of oh8Gua as template causing G----T substitutions and misincorporation of Oh8G Hua as substrate causing A----C substitutions, both caused by oh8 Gua.
Preparation and characterization of
TL;DR: In this article, the performance and productivity of the ~-cyclodextrin (CD) membrane reactor indicate an improvement of CD stability, and the effect of different average degree of ~-CD carbonate substitution (DS), the amount of immobilized carbonate and operating stirring speeds have been examined under a constant substrate concentration and constant permeation rate.
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The Allium test as a standard in environmental monitoring
TL;DR: The Allium test is a short-term test with many advantages: low cost, ease to handle, good chromosome conditions for the study of chromosome damage or disturbance of cell division including the evaluation of risks of aneuploidy.