Journal ArticleDOI
Glyoxalase-I activity and cell cycle regulation in yeast
TLDR
Results demonstrate that although glyoxalase-I activity is a good indicator of cell growth status, it is not involved in cell cycle regulation of this eukaryotic organism.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1984-03-30. It has received 18 citations till now. The article focuses on the topics: Saccharomyces cerevisiae & Cell growth.read more
Citations
More filters
Journal ArticleDOI
The glyoxalase system: new developments towards functional characterization of a metabolic pathway fundamental to biological life.
TL;DR: Investigation has brought new developments in the involvement of the glyoxalase in cell growth and vesicle mobilization, with increasing evidence of changes in the gly oxalase system during tumor growth and diabete mellitus, particularly relating to the development of associated clinical complications.
Book ChapterDOI
Metabolism and functions of glutathione in micro-organisms.
Michel Penninckx,Marc Elskens +1 more
TL;DR: GSH plays an important role in cellular protection during chemical stresses in spite of the fact that key enzymes of detoxification, such as GSH peroxidase and GSH S-transferase, remain at a low level.
Journal ArticleDOI
Molecular characterization of glyoxalase-I from a higher plant; upregulation by stress
TL;DR: The increased expression of glyoxalase-I may be linked to a higher demand for ATP generation and to enhanced glycolysis in salt-stressed plants.
Journal ArticleDOI
Metabolism of 2-oxoaldehyde in yeasts. Purification and characterization of NADPH-dependent methylglyoxal-reducing enzyme from Saccharomyces cerevisiae.
Kousaku Murata,Yasuki Fukuda,Makoto Simosaka,Kunihiko Watanabe,Toshihiko Saikusa,Akira Kimura +5 more
TL;DR: An enzyme catalyzing the reduction of methylglyoxal was isolated from Saccharomyces cerevisiae and its enzymatic properties were analyzed and it was tentatively designated the enzyme methyl glyoxal reductase.
References
More filters
Journal ArticleDOI
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
TL;DR: This assay is very reproducible and rapid with the dye binding process virtually complete in approximately 2 min with good color stability for 1 hr with little or no interference from cations such as sodium or potassium nor from carbohydrates such as sucrose.
Journal ArticleDOI
Sequential gene function in the initiation of Saccharomyces cerevisiae DNA synthesis
TL;DR: Experiments involving the shift of mutant cells from the restrictive to the permissive temperature in the presence of cycloheximide demonstrated that the protein synthesis requirement for yeast DNA replication can be completed before the cdc 7-mediated step.
Journal ArticleDOI
Regulation of mating in the cell cycle of Saccharomyces cerevisiae.
Brian J. Reid,Leland H. Hartwell +1 more
TL;DR: It is suggested that mating can occur from the cdc 28 step, the same step at which mating factors arrest cell cycle progress.
Journal ArticleDOI
Glyoxalase I, a zinc metalloenzyme of mammals and yeast.
TL;DR: Glyoxalase I from human and porcine erythrocytes, rat liver, and yeast was shown to contain zinc in a stoichiometry of about 1 mole per mole of enzyme subunit.
Journal ArticleDOI
RNA synthesis and control of cell division in the yeast S. cerevisiae.
G.C. Johnston,R.A. Singer +1 more
TL;DR: RNA metabolism must have a key role in the regulation of the cell cycle when exposed to chelating agents o-phenanthroline or 8-hydroxyquinoline, and the primary effect of these agents is on rRNA synthesis.