Journal ArticleDOI
Hemlock alkaloids from Socrates to poison aloes
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TLDR
Hemlock (Conium maculatum L. Umbelliferae) has long been known as a poisonous plant and toxicity is due to a group of piperidine alkaloids of which the representative members are coniine and gamma-coniceine.About:
This article is published in Phytochemistry.The article was published on 2005-06-01. It has received 128 citations till now. The article focuses on the topics: Conium maculatum & Coniine.read more
Citations
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Enantiomeric natural products: occurrence and biogenesis.
Jennifer M. Finefield,David H. Sherman,Martin Kreitman,Robert M. Williams,Robert M. Williams +4 more
TL;DR: In nature, chiral natural products are usually produced in optically pure form-however, occasionally both enantiomers are formed; these enantiomeric natural products can arise from a single species or from different genera and/or species.
Journal ArticleDOI
Enantioselective organocatalytic intramolecular aza-Michael reaction: a concise synthesis of (+)-sedamine, (+)-allosedamine, and (+)-coniine.
TL;DR: The intramolecular aza-Michael reaction of carbamates bearing remote alpha,beta-unsaturated aldehydes under organocatalytic conditions took place with good yields and excellent ee's when Jørgensen catalyst IV was used in the process, giving rise to the enantioselective formation of several five- and six-membered heterocycles.
Journal ArticleDOI
Quaternary centres bearing nitrogen (α-tertiary amines) as products of molecular rearrangements
TL;DR: The scope, limitations and specificities of some of these rearrangements of quaternary centres bearing a nitrogen substituent are reviewed in order to illuminate their synthetic potential.
Journal ArticleDOI
Progress and renewal in gustation: new insights into taste bud development.
TL;DR: How taste buds are established during development is discussed, highlighting the cellular and molecular mechanisms governing taste cell formation and turnover and how these findings aid the understanding of how and why many cancer therapies result in taste dysfunction.
Journal ArticleDOI
Principles of pharmacological research of nutraceuticals.
Ruth Andrew,Angelo A. Izzo +1 more
TL;DR: This article is part of a themed section on Principles of Pharmacological Research of Nutraceuticals, which highlights the need to understand more fully the role of phosphorous in the human immune system.
References
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The new life of a centenarian: signalling functions of NAD(P).
TL;DR: The comprehensive molecular characterization of NAD biosynthetic pathways over the past few years has further extended the understanding of the multiple roles of pyridine nucleotides in cell biology.
Related Papers (5)
Biochemistry of hemlock (Conium maculatum L.) alkaloids and their acute and chronic toxicity in livestock. A review.
T.A López,M.S Cid,M.L Bianchini +2 more