Journal ArticleDOI
Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti-inflammation and inhibition of lipogenesis in C57BL/6J mice.
TLDR
Results suggested that MWE prevents alcohol-induced liver injury through the activation of the AMPK and PPAR-α signal, mediated by multiple pathways, including reduced lipid accumulation and lipid synthesis, increased fatty acid transport and fatty acid oxidation responses, decreased oxidative stress and facilitated anti- inflammation.About:
This article is published in Food and Chemical Toxicology.The article was published on 2013-12-01. It has received 70 citations till now. The article focuses on the topics: Lipogenesis & Liver injury.read more
Citations
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Journal ArticleDOI
The Mulberry (Morus alba L.) Fruit—A Review of Characteristic Components and Health Benefits
Qingxia Yuan,Longyan Zhao +1 more
TL;DR: Recent findings regarding the chemical constituents and biological activities of mulberry fruit are provided, which may be useful for stimulating deep research of mulberries and for predicting their uses as important and safe contributors to benefit human health.
Journal ArticleDOI
Flavan‐3‐ols, anthocyanins, and inflammation
Pedro Mena,Raúl Domínguez-Perles,Amadeo Gironés-Vilaplana,Nieves Baenas,Cristina García-Viguera,Débora Villaño +5 more
TL;DR: In vitro studies performed with parental compounds at doses exceeding to those found in vivo may be drawing erroneous conclusions about their real efficacy, and future research should be focused on the understanding of dose/flavonoid intake–response relationship with pharmacokinetic studies, evaluating proper biomarkers of intake.
Journal ArticleDOI
Precooling and ozone treatments affects postharvest quality of black mulberry (Morus nigra) fruits.
TL;DR: From the analysis of cell ultrastructure and cell wall components of fruit, ozone and precooling treatments also induced shrinkage of the stomata in the epidermis, inhibited bacteria invasion, reduced water transpiration, and delayed the decomposition of the cell walls and the degradation of epidermal tissues.
Journal ArticleDOI
Cryptotanshinone from the Salvia miltiorrhiza Bunge Attenuates Ethanol-Induced Liver Injury by Activation of AMPK/SIRT1 and Nrf2 Signaling Pathways
TL;DR: Overall, CT exhibits a hepatoprotective effect against ethanol-induced liver injury by the inhibition of lipogenesis, oxidative stress, and inflammation through the activation of AMPK/SIRT1 and Nrf2 and the inhibiting of CYP2E1.
Journal ArticleDOI
Natural Products for Prevention and Treatment of Chemical-Induced Liver Injuries
TL;DR: This review summarizes the natural products and bioactive compounds with protective effects on liver injuries caused by chemicals, and special attention is paid to the mechanisms of action.
References
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Journal ArticleDOI
A simple method for the isolation and purification of total lipides from animal tissues.
TL;DR: In this paper, the authors described a simplified version of the method and reported the results of a study of its application to different tissues, including the efficiency of the washing procedure in terms of the removal from tissue lipides of some non-lipide substances of special biochemical interest.
Book ChapterDOI
Catalase in vitro
TL;DR: In this article, the catalytic activity of catalase has been investigated using ultraviolet (UV) spectrophotometry and Titrimetric methods, which is suitable for comparative studies for large series of measurements.
Book ChapterDOI
Microsomal lipid peroxidation.
John A. Buege,Steven D. Aust +1 more
TL;DR: This chapter discusses microsomal lipid peroxidation, a complex process known to occur in both plants and animals that involves the formation and propagation of lipid radicals, the uptake of oxygen, a rearrangement of the double bonds in unsaturated lipids, and the eventual destruction of membrane lipids.
Journal ArticleDOI
Involvement of the Superoxide Anion Radical in the Autoxidation of Pyrogallol and a Convenient Assay for Superoxide Dismutase
TL;DR: The autoxidation of pyrogallol was investigated in the presence of EDTA in the pH range 7.9–10.6, indicating an almost total dependence on the participation of the superoxide anion radical, O2·−, in the reaction.
Journal ArticleDOI
The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals
TL;DR: In this article, it was shown that mulberry leaves contain at least four flavonoids, two of which are rutin and quercetin, and that the scavenging effects of most mulberry extracts were greater than those of rutins (52.0%) at a concentration of 5μg ml −1.
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Alcoholic liver disease: pathogenesis and new targets for therapy.
José Altamirano,Ramon Bataller +1 more