Journal ArticleDOI
How can the brain's resting state activity generate hallucinations? A ‘resting state hypothesis’ of auditory verbal hallucinations
Georg Northoff,Pengmin Qin +1 more
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TLDR
The 'resting state hypotheses' of AVH suggest that AVH may be traced back to abnormally elevated resting state activity in auditory cortex itself, abnormal modulation of the auditory cortex by anterior cortical midline regions as part of the default-mode network, and neural confusion between auditory cortical resting state changes and stimulus-induced activity.About:
This article is published in Schizophrenia Research.The article was published on 2011-04-01. It has received 173 citations till now. The article focuses on the topics: Resting state fMRI & Auditory cortex.read more
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Clarifying the self: Response to Northoff
TL;DR: In this paper, the relation between self-related processing and brain activity was investigated and the nature of subjectivity was also discussed in the context of self-attention and subjectivity.
Investigating Brain Networks Associated with Insight in Adolescents at Ultra High-Risk for Schizophrenia
TL;DR: This is the first study to relate major brain networks to insight before the onset of psychosis, and is consistent with models proposing that different facets of insight are related to self-awareness and executive functioning through networks associated with these processes.
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Inhibitory Top-Down Control Deficits in Schizophrenia With Auditory Verbal Hallucinations: A Go/NoGo Task
TL;DR: In this paper, the authors employed event-related potentials to investigate the N2 and P3 amplitude and latency differences among these participants during a Go/NoGo task, and found that AVH patients had worse inhibitory top-down control, which might be involved in the occurrence of AVH.
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Diminished self-monitoring in hallucinations – Aberrant anterior insula connectivity differentiates auditory hallucinations in schizophrenia from subjective tinnitus
TL;DR: Focusing on predefined self-related regions-of-interest, it was found that SCZ-AH had reduced degree centrality in the right anterior insula (rAI) compared to both TN and healthy controls, and functional connectivity analysis showed a reduced connectivity between the rAI and right superior temporal gyrus.
References
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Journal ArticleDOI
A default mode of brain function.
Marcus E. Raichle,Ann Mary MacLeod,Abraham Z. Snyder,William J. Powers,Debra A. Gusnard,Gordon L. Shulman +5 more
TL;DR: A baseline state of the normal adult human brain in terms of the brain oxygen extraction fraction or OEF is identified, suggesting the existence of an organized, baseline default mode of brain function that is suspended during specific goal-directed behaviors.
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The Brain's Default Network Anatomy, Function, and Relevance to Disease
TL;DR: Past observations are synthesized to provide strong evidence that the default network is a specific, anatomically defined brain system preferentially active when individuals are not focused on the external environment, and for understanding mental disorders including autism, schizophrenia, and Alzheimer's disease.
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Medial prefrontal cortex and self-referential mental activity: Relation to a default mode of brain function
TL;DR: The presence of self-referential mental activity appears to be associated with increases from the baseline in dorsal MPFC, and reductions in ventral MPFC occurred consistent with the fact that attention-demanding tasks attenuate emotional processing.
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Self-referential processing in our brain--a meta-analysis of imaging studies on the self.
Georg Northoff,Alexander Heinzel,Moritz de Greck,Felix Bermpohl,Felix Bermpohl,Henrik Dobrowolny,Jaak Panksepp +6 more
TL;DR: It is concluded that self-referential processing in CMS constitutes the core of the authors' self and is critical for elaborating experiential feelings of self, uniting several distinct concepts evident in current neuroscience.
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The mismatch negativity (MMN) in basic research of central auditory processing: a review.
TL;DR: The mismatch negativity (MMN) enables one to establish the brain processes underlying the initiation of attention switch to, conscious perception of, sound change in an unattended stimulus stream.