Journal ArticleDOI
Hydroxylation of aromatic hydrocarbons in the rat
Olav M. Bakke,Ronald R. Scheline +1 more
TLDR
The hydroxylation of benzene, toluene, ethylbenzene, styrene, cumene, o -xylene, m -xylene, p -Xylene, p-cymene, pseudocumene, and mesitylene was studied following their oral administration to rats to study the formation of phenolic metabolites to the toxicity of aromatic hydrocarbons.About:
This article is published in Toxicology and Applied Pharmacology.The article was published on 1970-05-01. It has received 164 citations till now. The article focuses on the topics: Xylene & Ethylbenzene.read more
Citations
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Journal ArticleDOI
Hepatic microsomal oxidation of styrene to 4-hydroxystyrene 7,8-glycol via 4-hydroxystyrene and its 7,8-oxide as short-lived intermediates.
Journal ArticleDOI
Stereometabolism of styrene in man. Urinary excretion of chiral styrene metabolites.
TL;DR: In this article, a typical time-dependent urinary concentration profile of one person over a 49-h period is presented and compared with the results of a previous study of occupationally exposed workers and an unexposed control group.
Book ChapterDOI
Gas Chromatographic - Mass Spectrometric Studies on Styrene Toxicity
TL;DR: In this article, a series of analytical techniques are described which may give a deeper insight into the mechanisms of styrene toxicity, including ultraviolet (UV) photometry, thin layer chromatography, liquid scintillation counting (LSC), gas liquid chromatography (GLC), mass spectrometry (MS), mass fragmentography (MF), and mass chromatography(MC).
Public Health Goal for BENZENE In Drinking Water
TL;DR: The Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency announces the availability of the final technical support document for the Public Health Goal (PHG) for benzene in drinking water.
Journal ArticleDOI
Dietary and ethanol induced alterations of the toxikokinetics of toluene in humans.
TL;DR: The results indicated that subacute ethanol consumption combined with a carbohydrate restricted diet, may enhance the metabolism of toluene in humans at an exposure concentration of 200 mg/m3.
References
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Journal ArticleDOI
Decarboxylation and demethylation of some phenolic benzoic acid derivatives by rat caecal contents.
TL;DR: Rat caecal contents decarboxylate phenolic benzoic acid derivatives when a free hydroxyl group is in the para position but the presence of substituents adjacent to this group or the carboxyl group reduce or abolish the reaction.
Journal ArticleDOI
Kinetic studies of the metabolism of foreign organic compounds. 1. The formation of benzoic acid from benzamide, toluene, benzyl alcohol and benzaldehyde and its conjugation with glycine and glucuronic acid in the rabbit
H. G. Bray,W. V. Thorpe,K. White +2 more