Journal ArticleDOI
Hypoglycemic activity of withanolides and elicitated Withania somnifera.
TLDR
In this paper, the anti-diabetic activity of W. somnifera extract and purified withanolides, as well as the effect of various elicitors on this activity were evaluated.About:
This article is published in Phytochemistry.The article was published on 2015-08-01. It has received 72 citations till now. The article focuses on the topics: Withania somnifera & Withaferin A.read more
Citations
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Journal ArticleDOI
Antidiabetic Potential of Medicinal Plants and Their Active Components.
Bahare Salehi,Athar Ata,Nanjangud V. Anil Kumar,Farukh Sharopov,Karina Ramírez-Alarcón,Ana M. Ruiz-Ortega,Seyed Abdulmajid Ayatollahi,Patrick Valere Tsouh Fokou,Farzad Kobarfard,Zainul Amiruddin Zakaria,Zainul Amiruddin Zakaria,Marcello Iriti,Yasaman Taheri,Miquel Martorell,Antoni Sureda,William N. Setzer,Alessandra Durazzo,Massimo Lucarini,Antonello Santini,Raffaele Capasso,Elise Adrian Ostrander,Atta-ur-Rahman,Muhammad Iqbal Choudhary,William C. Cho,Javad Sharifi-Rad +24 more
TL;DR: Examples of medicinal plants with antidiabetic potential are described, with focuses on preclinical and clinical studies.
Journal ArticleDOI
Improving production of plant secondary metabolites through biotic and abiotic elicitation
TL;DR: Different elicitation methods through various biotic (proteins, carbohydrates, plant growth promoting rhizobacteria, fungus, hormones) and abiotic elicitors that could bring about increased yield of secondary metabolites especially in medicinal plants beneficial to the medicinal and aromatic industry are discussed.
Journal ArticleDOI
Pharmacologic overview of Withania somnifera, the Indian Ginseng
TL;DR: Withania somnifera is a potential drug candidate to treat various clinical conditions, particularly related to the nervous system, and the mechanisms of action and potential therapeutic applications of the plant and its active constituents are discussed.
Journal ArticleDOI
Interplay between chemistry and morphology in medical cannabis (Cannabis sativa L.)
TL;DR: In this paper, the authors investigated the interplay between chemical profiles (of cannabinoids and the ionome) and local locations in the plant body and found that the concentration of cannabinoids in the inflorescence leaves is considerable and for THC and CBD reached about half of that found in flowers.
Journal ArticleDOI
Withania somnifera (L.) Dunal (Ashwagandha): A comprehensive review on ethnopharmacology, pharmacotherapeutics, biomedicinal and toxicological aspects.
Subhabrata Paul,Shreya Chakraborty,Uttpal Anand,Swarnali Dey,Samapika Nandy,Mimosa Ghorai,Suchismita Chatterjee Saha,Manoj Patil,Ramesh Kandimalla,Jarosław Proćków,Abhijit Dey +10 more
TL;DR: In this article, a comprehensive summary of the geographical distribution, traditional use, phytochemistry, and pharmacological activities of W. somnifera and its active constituents are presented.
References
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Journal ArticleDOI
Stress-Induced Phenylpropanoid Metabolism.
Richard A. Dixon,Nancy L. Paiva +1 more
TL;DR: Limiting discussion to stress-induced phenylpropanoids eliminates few of the structural classes, because many compounds that are constitutive in one plant species or tissue can be induced by various stresses in another species or in another tissue of the same plant.
Journal Article
Scientific basis for the therapeutic use of Withania somnifera (ashwagandha): a review.
TL;DR: Preliminary studies have found various constituents of ashwagandha exhibit a variety of therapeutic effects with little or no associated toxicity, indicating this herb should be studied more extensively to confirm these results and reveal other potential therapeutic effects.
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ALKALOID BIOSYNTHESIS IN PLANTS: Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications.
TL;DR: The early events of signal perception, the pathways of signal transduction, and the function of gene promoters have been studied in relation to the regulation of alkaloid metabolism.
Journal ArticleDOI
Chitosan in plant protection
TL;DR: This review recapitulates the properties and uses of chitin, chitosan, and their derivatives, and will focus on their applications and mechanisms of action during plant-pathogen interactions.
Journal ArticleDOI
Steroidal lactones from Withania somnifera, an ancient plant for novel medicine.
TL;DR: An overview of the chemical structures of triterpenoid components and their biological activity is presented, focusing on two novel activities, tumor inhibition and antiangiogenic properties of withaferin A and the effects of withanolide A on Alzheimer's disease.