Journal ArticleDOI
Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas.
Yannick Gueguen,Jean-Paul Cadoret,Didier Flament,Catherine Barreau-Roumiguière,Anne Laure Girardot,Julien Garnier,Alixe Hoareau,Evelyne Bachère,Jean Michel Escoubas +8 more
TLDR
An expressed sequence tag program to isolate genes involved in defense mechanisms of the Pacific oyster, Crassostrea gigas, identified 20 genes that may be implicated in immune function and investigated the expression of four of them during bacterial challenge of oysters.About:
This article is published in Gene.The article was published on 2003-01-16. It has received 237 citations till now. The article focuses on the topics: Pacific oyster & Crassostrea.read more
Citations
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Journal ArticleDOI
Insights into the anti-microbial defense of marine invertebrates: the penaeid shrimps and the oyster Crassostrea gigas
Evelyne Bachère,Yannick Gueguen,Marcelo Gonzalez,Julien de Lorgeril,Julien Garnier,Bernard Romestand +5 more
TL;DR: Genomics and gene profiling are promising to deepen the understanding of the anti‐microbial defense of the oyster and the shrimp, but real progress will depend also on the characterization of hemocyte lineages and hematopoiesis of these marine invertebrates as well as on the ontogenesis of their immune systems.
Journal ArticleDOI
Matrix Metalloproteinases in Lung: Multiple, Multifarious, and Multifaceted
TL;DR: While inhibition of MMPs has been proposed as a therapeutic option in a variety of inflammatory lung conditions, a complete understanding of the biology of these complex enzymes is needed before the authors can reasonably consider them as therapeutic targets.
Journal ArticleDOI
Transcriptome and proteome analysis of Pinctada margaritifera calcifying mantle and shell: focus on biomineralization
Caroline Joubert,David Piquemal,Benjamin Marie,Laurent Manchon,Fabien Pierrat,Isabelle Zanella-Cléon,Nathalie Cochennec-Laureau,Yannick Gueguen,Caroline Montagnani +8 more
TL;DR: This EST study made on the calcifying tissue of P. margaritifera is the first description of pyrosequencing on a pearl-producing bivalve species, and represents a major breakthrough in the field of molluskan biomineralization.
Journal ArticleDOI
Macroarray analysis of coelomocyte gene expression in response to LPS in the sea urchin. Identification of unexpected immune diversity in an invertebrate
TL;DR: It is proposed that this set of transcripts encodes a family of putative immune response proteins that may represent a major component of an immunological response to bacterial challenge.
Journal ArticleDOI
Discovery of genes expressed in response to Perkinsus marinus challenge in Eastern (Crassostrea virginica) and Pacific (C. gigas) oysters
TL;DR: Results of this study highlighted some differences in gene expression between the two oysters in response to P. marinus infection, providing candidate genes and pathways for further analysis.
References
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CAP3: A DNA Sequence Assembly Program
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The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
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