Journal ArticleDOI
Immune system stimulation by probiotic microorganisms.
Rabia Ashraf,Nagendra P. Shah +1 more
TLDR
This review is presented to provide detailed informations about how probiotics stimulate the authors' immune system and to improve the gut mucosal immune system by increasing the number of IgA+ cells and cytokine-producing cells in the effector site of the intestine.Abstract:
Probiotic organisms are claimed to offer several functional properties including stimulation of immune system. This review is presented to provide detailed informations about how probiotics stimulate our immune system. Lactobacillus rhamnosus GG, Lactobacillus casei Shirota, Bifidobacterium animalis Bb-12, Lactobacillus johnsonii La1, Bifidobacterium lactis DR10, and Saccharomyces cerevisiae boulardii are the most investigated probiotic cultures for their immunomodulation properties. Probiotics can enhance nonspecific cellular immune response characterized by activation of macrophages, natural killer (NK) cells, antigen-specific cytotoxic T-lymphocytes, and the release of various cytokines in strain-specific and dose-dependent manner. Mixture and type (gram-positive and gram-negative) of probiotic organisms may induce different cytokine responses. Supplementation of probiotic organisms in infancy could help prevent immune-mediated diseases in childhood, whereas their intervention in pregnancy could affect...read more
Citations
More filters
Journal ArticleDOI
Bifidobacteria exert strain‐specific effects on stress‐related behavior and physiology in BALB/c mice
TL;DR: The effects of two different Bifidobacteria on anxiety and depression‐like behavior were compared and an antidepressant was also used as a comparator.
Journal ArticleDOI
Benefits and Inputs From Lactic Acid Bacteria and Their Bacteriocins as Alternatives to Antibiotic Growth Promoters During Food-Animal Production.
Nuria Vieco-Saiz,Yanath Belguesmia,Ruth Raspoet,Eric Auclair,Frédérique Gancel,Isabelle Kempf,Djamel Drider +6 more
TL;DR: This review aimed at underlining the benefits and inputs from LAB as potential alternatives to antibiotics in poultry, pigs, ruminants, and aquaculture production.
Journal ArticleDOI
Health Benefits of Heat-Killed (Tyndallized) Probiotics: An Overview.
TL;DR: Data indicate that heat-killed bacteria or their fractions or purified components have key probiotic effects, with advantages versus live probiotics (mainly their safety profile), positioning them as interesting strategies for the management of common prevalent conditions in a wide variety of patients´ characteristics.
Journal ArticleDOI
Potential role of the intestinal microbiota in programming health and disease.
TL;DR: Based on recent advances, modulation of gut microbiota with probiotics, prebiotics, or fermented dairy products has been suggested as a treatment of, or prevention for, different disorders such as IBS, infectious diarrhea, allergic disease, and necrotizing enterocolitis.
Journal ArticleDOI
Probiotics modulate gut microbiota and improve insulin sensitivity in DIO mice.
Renata A. Bagarolli,Natalia Tobar,Alexandre G. Oliveira,Tiago Gomes Araújo,Bruno M. Carvalho,Guilherme Z. Rocha,Juliana Falcato Vecina,Kelly L Calisto,Dioze Guadagnini,Patrícia O. Prada,Andrey Santos,Sara T.O. Saad,Mario J.A. Saad +12 more
TL;DR: The data demonstrate that the intestinal microbiome is a key modulator of inflammatory and metabolic pathways in both peripheral and central tissues and shed light on probiotics as an important tool to prevent and treat patients with obesity and insulin resistance.
References
More filters
Journal ArticleDOI
Modulation of natural killer cell activity by viruses.
TL;DR: The evidence has been accumulated supporting the role of viral immunoevasion of NK cells in viral pathogenesis in vivo and the existence of plethora of viral mechanisms aimed to modulate their function.
Journal ArticleDOI
Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut
TL;DR: A cardinal role for epithelial cells is identified in sampling the intestinal microenvironment, discriminating pathogenic and commensal microorganisms and influencing the function of antigen-presenting cells and lymphocytes.
Journal ArticleDOI
Probiotics: an overview of beneficial effects
TL;DR: Results from well conducted clinical studies will expand and increase the acceptance of probiotics for the treatment and prevention of selected diseases.
Journal ArticleDOI
Probiotics: effects on immunity
TL;DR: The data show that probiotics can be used as innovative tools to alleviate intestinal inflammation, normalize gut mucosal dysfunction, and down-regulate hypersensitivity reactions and suggest that specific immunomodulatory properties of probiotic bacteria should be characterized when developing clinical applications for extended target populations.
Journal ArticleDOI
Lactobacilli Differentially Modulate Expression of Cytokines and Maturation Surface Markers in Murine Dendritic Cells
TL;DR: The results suggest that different species of Lactobacillus exert very different DC activation patterns and, furthermore, at least one species may be capable of inhibiting activities of other species in the genus.
Related Papers (5)
A human gut microbial gene catalogue established by metagenomic sequencing
Junjie Qin,Ruiqiang Li,Jeroen Raes,Manimozhiyan Arumugam,Kristoffer Sølvsten Burgdorf,Chaysavanh Manichanh,Trine Nielsen,Nicolas Pons,Florence Levenez,Takuji Yamada,Daniel R. Mende,Junhua Li,Junming Xu,Shaochuan Li,Dongfang Li,Jianjun Cao,Bo Wang,Huiqing Liang,Huisong Zheng,Yinlong Xie,Julien Tap,Patricia Lepage,Marcelo Bertalan,Jean-Michel Batto,Torben Hansen,Denis Le Paslier,Allan Linneberg,H. Bjørn Nielsen,Eric Pelletier,Pierre Renault,Thomas Sicheritz-Pontén,Keith Turner,Hongmei Zhu,Chang Yu,Shengting Li,Min Jian,Yan Zhou,Yingrui Li,Xiuqing Zhang,Songgang Li,Nan Qin,Huanming Yang,Jian Wang,Søren Brunak,Joël Doré,Francisco Guarner,Karsten Kristiansen,Oluf Pedersen,Julian Parkhill,Jean Weissenbach,Peer Bork,S. Dusko Ehrlich,Jun Wang +52 more