Journal ArticleDOI
Immunoglobulin G4-Related Disease
Su Jin Moon,Jun-Ki Min +1 more
TLDR
Rituximab is reported to be an effective therapy for treatment of IgG4-RD, even without concomitant glucocorticoid therapy, which is the first-line therapy for patients with multiple organ dysfunction and clinical symptoms.Citations
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Immunoglobulin G4-related disease in the stomach presenting as a gastric subepithelial tumor: Case report.
Min Ji Cho,Hee Seok Moon,Hyeon Seok Lee,Jae Ho Park,Ju Seok Kim,Sun Hyung Kang,Eaum Seok Lee,Seok Hyun Kim,Jae Kyu Sung,Byung Seok Lee,Hyun Yong Jeong +10 more
TL;DR: Using alternative preoperative diagnostic methods such as endoscopic ultrasound-guided fine-needle biopsy or the biopsy unroofing technique could spare the patient from unnecessary surgical treatment.
References
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Journal ArticleDOI
Decreased B cell activating factor receptor expression on peripheral lymphocytes associated with increased disease activity in primary Sjögren’s syndrome and systemic lupus erythematosus
Jérémie Sellam,Corinne Miceli-Richard,Jacques-Eric Gottenberg,Marc Ittah,Frédéric Lavie,Christine Lacabaratz,Nicolas Gestermann,Alexis Proust,Olivier Lambotte,Xavier Mariette +9 more
TL;DR: BAFF-R expression is reduced on peripheral B cells of patients with pSS and SLE and down-regulation occurs through a post-transcriptional mechanism and could be the consequence of chronic increase in BAFF.
Journal ArticleDOI
Anti-neutrophil cytoplasm antibody IgG subclasses in Wegener's granulomatosis: a possible pathogenic role for the IgG4 subclass
TL;DR: The stimulation of superoxide release by IgG1‐ and IgG3‐ANCA subclass fractions is consistent with the proposed mechanism of co‐ligation of PR3 antigen and FcγRIIa/IIIb receptors, however, the demonstration of similar activity for the IgG4‐AN CA subclass fractions isolated from some sera was unexpected.
Journal ArticleDOI
The pathology of IgG4-related disease: critical issues and challenges
TL;DR: This review aims to provide the histopathologist with a set of practical guidelines for the diagnosis of IgG4-RD, and also addresses the many controversies associated with the diagnostic aspects of this disease.
Journal ArticleDOI
IgG4- related disease: an orphan disease with many faces
TL;DR: Current knowledge on clinical manifestations, pathophysiology and treatment of IgG4-RD is summarized, although adjunctive immunosuppressive agents are used in relapsing patients.
Journal ArticleDOI
Fibrosing variant of Hashimoto thyroiditis is an IgG4 related disease
Vikram Deshpande,Amelia Huck,Esther M.M. Ooi,John H. Stone,William C. Faquin,G. Petur Nielsen +5 more
TL;DR: Although a proportion of cases of HT show elevated numbers of IgG4 positive plasma cells, these cases lack the histological features typically associated with IgG 4-RD, and thus the relationship between HT and IgG3-RD remains unproven.