Journal ArticleDOI
Improving embryo selection using a computer-automated time-lapse image analysis test plus day 3 morphology: results from a prospective multicenter trial
Joe Conaghan,A.A. Chen,S.P. Willman,K. Ivani,Philip E. Chenette,Robert Boostanfar,Valerie L. Baker,G. David Adamson,Mary E. Abusief,M. Gvakharia,Kevin E. Loewke,Shehua Shen +11 more
TLDR
Experienced embryologists using Eeva in combination with D3 morphology significantly improved their ability to identify embryos that would reach the usable blastocyst stage, and adjunctive use of morphology plus Eeva also reduced interindividual variability in embryo selection.About:
This article is published in Fertility and Sterility.The article was published on 2013-08-01. It has received 261 citations till now. The article focuses on the topics: Blastocyst Transfer.read more
Citations
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Journal ArticleDOI
Local Binary Convolutional Neural Networks' Long Short-Term Memory Model for Human Embryos' Anomaly Detection
TL;DR: In this article , the authors presented a novel deep learning approach to distinguish simultaneous abnormality of embryos in time-lapse systems for detecting live and non-live births in IVF.
Limitações e controvérsias na determinação do valor preditivo de critérios de morfologia oocitária e embrionária Limitations and controversies in determining the predictive value of oocyte and embryo morphology criteria
TL;DR: A otimizacao da selecao embrionaria representa um grande potencial de aumento das taxas de sucesso do tratamento, tornando extremamente dificil a implementacao de um consenso do valor preditivo dos diferentes parâmetros morfologicos avaliados.
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The KIDScore™ D3 scoring system contributes to the prediction of embryonic development potential: A promising tool for screening high-quality embryos.
TL;DR: Using the KIDScoreTM D3 (KID3) scoring system, day 3 embryos observed by time-lapse imaging (TLI) were scored to explore the predictive value of KID scoring system on the developmental potential of embryos as mentioned in this paper .
References
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Journal ArticleDOI
Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer
TL;DR: The ability to transfer one high-scoring blastocyst should lead to pregnancy rates greater than 60%, without the complication of twins, according to a retrospective review of blastocysts transfer in an IVF clinic.
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The use of morphokinetics as a predictor of embryo implantation
TL;DR: A multivariable model is proposed based on the findings to classify embryos according to their probability of implantation and it is proposed that the image acquisition and time-lapse analysis system makes it possible to determine exact timing of embryo cleavages in a clinical setting.
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Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
Wong Connie C,Kevin E. Loewke,Nancy L. Bossert,Barry Behr,Christopher J. De Jonge,Thomas M. Baer,Renee A. Reijo Pera +6 more
TL;DR: It is found that success in progression to the blastocyst stage can be predicted with >93% sensitivity and specificity by measuring three dynamic, noninvasive imaging parameters by day 2 after fertilization, before embryonic genome activation (EGA).
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Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography.
TL;DR: Time-lapse video cinematography is shown to be an excellent tool for studying fertilization and early embryo development, and it was found that good quality embryos arose from oocytes that had more uniform timing from injection to pronuclear abuttal and tended to have a longer cytoplasmic wave.
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Epigenetics and assisted reproductive technology: a call for investigation.
TL;DR: The need for investigation of two major questions is highlighted: large-scale case-control studies of ART outcomes, including long-term assessment of the incidence of birth defects and cancer, and investigation of the relationship between epigenetic errors in both offspring and parents.