Journal ArticleDOI
Improving embryo selection using a computer-automated time-lapse image analysis test plus day 3 morphology: results from a prospective multicenter trial
Joe Conaghan,A.A. Chen,S.P. Willman,K. Ivani,Philip E. Chenette,Robert Boostanfar,Valerie L. Baker,G. David Adamson,Mary E. Abusief,M. Gvakharia,Kevin E. Loewke,Shehua Shen +11 more
TLDR
Experienced embryologists using Eeva in combination with D3 morphology significantly improved their ability to identify embryos that would reach the usable blastocyst stage, and adjunctive use of morphology plus Eeva also reduced interindividual variability in embryo selection.About:
This article is published in Fertility and Sterility.The article was published on 2013-08-01. It has received 261 citations till now. The article focuses on the topics: Blastocyst Transfer.read more
Citations
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Journal ArticleDOI
Decision points for individualized hormonal stimulation with recombinant gonadotropins for treatment of women with infertility.
Bruno Lunenfeld,Wilma Bilger,Salvatore Longobardi,Jan Kirsten,Thomas D'Hooghe,Thomas D'Hooghe,Thomas D'Hooghe,Sesh Kamal Sunkara +7 more
TL;DR: This review considers the current state-of-the-art related to decision points during individualized treatment of female infertility, before looking at future developments that might further assist in making individualization treatment decisions, including the use of computer-assisted decision making.
Journal ArticleDOI
Revealing the secret life of pre-implantation embryos by time-lapse monitoring: A review
TL;DR: The findings from this review support common use of time-lapse monitoring in ART centers; but, future large studies assessing this system in well-designed trials are necessary.
Proceedings ArticleDOI
A unified graphical models framework for automated human embryo tracking in time lapse microscopy
Farshid Moussavi,Yu Wang,Peter Lorenzen,Jonathan D. Oakley,Daniel B. Russakoff,Stephen Gould +5 more
TL;DR: This work poses the mitosis detection problem as augmented simultaneous segmentation and classification in a conditional random field framework that combines tracking based and tracking free elements and shows significant improvement over a traditional particle filter.
Pre-treatment with ulipristal acetate before ICSI procedure: a case report Zastosowanie octanu uliprystalu przed procedur¹ ICSI: opis przypadku
TL;DR: In this paper, a 35-year-old woman reported to the Non-Public Health Care Unit “Ovum Reproduction and Andrology” in Lublin for continued treatment of infertility.
Journal ArticleDOI
Comparison of the morphokinetic parameters of embryos according to ovarian reserve in IVF cycles
TL;DR: Ovarian reserve and age of women did not seem to affect the morphokinetic parameters of embryos with a time-lapse monitoring system.
References
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Journal ArticleDOI
Blastocyst score affects implantation and pregnancy outcome: towards a single blastocyst transfer
TL;DR: The ability to transfer one high-scoring blastocyst should lead to pregnancy rates greater than 60%, without the complication of twins, according to a retrospective review of blastocysts transfer in an IVF clinic.
Journal ArticleDOI
The use of morphokinetics as a predictor of embryo implantation
TL;DR: A multivariable model is proposed based on the findings to classify embryos according to their probability of implantation and it is proposed that the image acquisition and time-lapse analysis system makes it possible to determine exact timing of embryo cleavages in a clinical setting.
Journal ArticleDOI
Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage
Wong Connie C,Kevin E. Loewke,Nancy L. Bossert,Barry Behr,Christopher J. De Jonge,Thomas M. Baer,Renee A. Reijo Pera +6 more
TL;DR: It is found that success in progression to the blastocyst stage can be predicted with >93% sensitivity and specificity by measuring three dynamic, noninvasive imaging parameters by day 2 after fertilization, before embryonic genome activation (EGA).
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Preliminary observations on polar body extrusion and pronuclear formation in human oocytes using time-lapse video cinematography.
TL;DR: Time-lapse video cinematography is shown to be an excellent tool for studying fertilization and early embryo development, and it was found that good quality embryos arose from oocytes that had more uniform timing from injection to pronuclear abuttal and tended to have a longer cytoplasmic wave.
Journal ArticleDOI
Epigenetics and assisted reproductive technology: a call for investigation.
TL;DR: The need for investigation of two major questions is highlighted: large-scale case-control studies of ART outcomes, including long-term assessment of the incidence of birth defects and cancer, and investigation of the relationship between epigenetic errors in both offspring and parents.