Incidence and clinical importance of perioperative histamine release: randomised study of volume loading and antihistamines after induction of anaesthesia
Wilfried Lorenz,Helmut Sitter,D. Weber,Matthias Rothmund,Benno Stinner,Dan G. Duda,W. F. Dick,H. Menke,Th. Junginger,A. Doenicke,Ch. Ohmann,A. Black,M.J.R. Healy +12 more
TLDR
The histamine-related disturbances under anaesthesia were remarkable for their severity (even with small rises in histamine concentrations), for the prevalence of bradycardia, and for the absence of skin signs.About:
This article is published in The Lancet.The article was published on 1994-04-16 and is currently open access. It has received 136 citations till now. The article focuses on the topics: Antihistamine & Haemaccel.read more
Citations
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How safe is gelatin? A systematic review and meta-analysis of gelatin-containing plasma expanders vs crystalloids and albumin
Claudia Moeller,Carolin Fleischmann,Daniel O. Thomas-Rueddel,Vlasislav Vlasakov,Bram Rochwerg,Philip Theurer,Luciano Gattinoni,Konrad Reinhart,Christiane S. Hartog +8 more
TL;DR: Until well-designed randomized controlled trials show that gelatin is safe, it is cautioned against the use of gelatins because cheaper and safer fluid alternatives are available.
Journal ArticleDOI
Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated with cardiac surgery.
Rick Davis,Ruth Whittington +1 more
TL;DR: The types and incidences of adverse events reported with aprotinin therapy are generally consistent with those associated with major cardiac surgery, and are not significantly different from those observed in control groups.
Journal ArticleDOI
Hemodilution in Clinical Surgery: State of the Art 1996
U. Kreimeier,Konrad Messmer +1 more
TL;DR: Hemodilution is feasible and relatively cost-effective, and it minimizes adverse effects associated with transfusion of homologous blood, particularly transmission of viral diseases, immunosuppression, and infectious complications.
Journal ArticleDOI
How can medical journals help prevent poor medical research? Some opportunities presented by electronic publishing
Iain Chalmers,Douglas G. Altman +1 more
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Anaphylactic reactions to aprotinin reexposure in cardiac surgery: Relation to antiaprotinin immunoglobulin G and E antibodies
Wulf Dietrich,Paul Späth,Michael Zühlsdorf,Harald Dalichau,P. G. Kirchhoff,Hermann Kuppe,Dieter U. Preiss,Gabriele Mayer +7 more
TL;DR: In this paper, the authors examined the incidence of anaphylactic reactions in patients reexposed to aprotinin and the relation to preformed antiaprotinin immunoglobulin (Ig)G and IgE antibodies.
References
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Randomisation and baseline comparisons in clinical trials.
TL;DR: 80 reports of randomised clinical trials in four leading general medical journals were reviewed and the reporting of the methodology of randomisation was inadequate, and the handling of comparisons of baseline characteristics was inadequate.
Journal ArticleDOI
Perioperative myocardial ischemia in patients undergoing noncardiac surgery—I: Incidence and severity during the 4 Day perioperative period☆
Dennis T. Mangano,Milton Hollenberg,Milton Hollenberg,G Fegert,G Fegert,M L Meyer,M L Meyer,Martin J. London,Martin J. London,Julio F. Tubau,Julio F. Tubau,W C Krupski,W C Krupski +12 more
TL;DR: The electrocardiographic changes consistent with ischemia during the 4 day perioperative period were documented and characterized in 100 patients with or at risk for coronary artery disease undergoing noncardiac surgery and postoperative ischemic episodes were the most severe.
Journal ArticleDOI
Anaphylactoid reactions during anaesthesia. Seven years' experience of intradermal testing
D. C. Galletly,B. C. Treuren +1 more
TL;DR: Pancuronium is suggested to be the least likely currently available agent to provoke a major anaphylactoid reaction and Predisposing factors in patients sensitive to muscle relaxants were: female sex, previous allergy and atopy.
Journal ArticleDOI
Human basophil/mast cell releasability. IX. Heterogeneity of the effects of opioids on mediator release.
Cristiana Stellato,Raffaele Cirillo,Amato de Paulis,Vincenzo Casolaro,Vincenzo Patella,P. Mastronardi,Basilio Mazzarella,Gianni Marone +7 more
TL;DR: The effects of increasing concentrations of three opioids were studied on the release of preformed and de novo synthesized chemical mediators from human peripheral blood basophils and mast cells isolated from skin tissues or lung parenchyma.
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Incidence and severity of anaphylactoid reactions to colloid volume substitutes
Johannes Ring,Konrad Messmer +1 more