Inhaler mishandling remains common in real life and is associated with reduced disease control
Andrea S. Melani,Marco Bonavia,Vincenzo Cilenti,Cristina Cinti,Marco Lodi,Paola Martucci,Maria Serra,Nicola Scichilone,Piersante Sestini,Maria Aliani,Margherita Neri +10 more
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TLDR
In this paper, the authors investigated the prevalence of inhaler mishandling in a large population of experienced patients referring to chest clinics; to analyze the variables associated with misuse and the relationship between inhaler handling and health-care resources use and disease control.About:
This article is published in Respiratory Medicine.The article was published on 2011-06-01 and is currently open access. It has received 681 citations till now. The article focuses on the topics: Dry-powder inhaler & Inhaler.read more
Citations
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Journal ArticleDOI
Effect of a spacer on total systemic and lung bioavailability in healthy volunteers and in vitro performance of the Symbicort® (budesonide/formoterol) pressurized metered dose inhaler
Michael Gillen,Pablo Forte,Jan Olof Svensson,Jan Olof Svensson,Rosa Lamarca,Joanna Burke,Karolina Rask,Ulrika Larsdotter Nilsson,Göran Eckerwall +8 more
TL;DR: The clinical study demonstrated that in subjects with poor inhalation technique the use of a spacer device can improve drug delivery in these patients, and the relative bioavailability of single doses of Symbicort® (budesonide/formoterol) pMDI 160/4.5 μg/actuation (2 actuations) used with and without a spacers was established.
Journal ArticleDOI
Improved laboratory test methods for orally inhaled products
Jolyon P. Mitchell,Mark Nagel +1 more
TL;DR: Advice is provided on approaches that may be helpful to develop clinically appropriate methods to assess OIP performance in the laboratory, with the ultimate goal of developing robust in vitro-in vivo relationships for the major inhaled drug classes.
Journal ArticleDOI
Frequent Outpatient Visits Prevent Exacerbation of Chronic Obstructive Pulmonary Disease.
Hye Jung Park,Min Kwang Byun,Taehee Kim,Chin Kook Rhee,Kyungjoo Kim,Bo Yeon Kim,Sang In Ahn,Yon U Jo,Kwang-Ha Yoo +8 more
TL;DR: It was showed frequent outpatient visits reduce the risk of COPD exacerbation by 45–60% and frequent visits were identified as an independent factor preventing COPd exacerbation that required admission to a ward, emergency room, or intensive care unit.
Journal ArticleDOI
Predictors of proper inhaler technique and asthma control in pediatric patients with asthma
TL;DR: In this article, a cross-sectional study was conducted in Jordan from February 2019 to February 2020 to assess the proper handling of asthma inhalers and asthma control in addition to factors influencing them among pediatric patients who self-administer their inhalers.
Journal ArticleDOI
Treatable Traits in COPD – A Proposed Approach
João Cardoso,António Jorge Ferreira,Miguel Guimarães,Ana Sofia Oliveira,Paula Simão,Maria Sucena +5 more
TL;DR: In this paper, a multidisciplinary model based on two distinct phases is proposed, with the potential to be implemented in both primary care and hospital settings, to reduce the risk of future exacerbations and improve the management of COPD exacerbations.
References
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
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Development of the asthma control test: A survey for assessing asthma control
Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
TL;DR: Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.
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Evaluation of Clinical Methods for Rating Dyspnea
TL;DR: The results show that the BDI, MRC scale, and OCD provide significantly related measures of Dyspnea, and the clinical ratings of dyspnea correlate significantly with physiologic parameters of lung function; and breathlessness may be related to the pathophysiology of the specific respiratory disease.
Journal ArticleDOI
Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
TL;DR: It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.
Journal ArticleDOI
Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
Violaine Giraud,Nicolas Roche +1 more
TL;DR: Misuse of pressurized metered-dose inhalers, which is mainly due to poor coordination, is frequent and associated with poorer asthma control in inhaled corticosteroid-treated asthmatics, highlighting the importance of evaluating inhalation technique and providing appropriate education in all patients.
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