Inhaler mishandling remains common in real life and is associated with reduced disease control
Andrea S. Melani,Marco Bonavia,Vincenzo Cilenti,Cristina Cinti,Marco Lodi,Paola Martucci,Maria Serra,Nicola Scichilone,Piersante Sestini,Maria Aliani,Margherita Neri +10 more
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In this paper, the authors investigated the prevalence of inhaler mishandling in a large population of experienced patients referring to chest clinics; to analyze the variables associated with misuse and the relationship between inhaler handling and health-care resources use and disease control.About:
This article is published in Respiratory Medicine.The article was published on 2011-06-01 and is currently open access. It has received 681 citations till now. The article focuses on the topics: Dry-powder inhaler & Inhaler.read more
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Stable COPD Treatment: Where are We?
TL;DR: The number of pharmacological treatments available for COPD has increased markedly in the last years, mostly corresponding to new agents, combinations and devices within know pharmacological classes, but these options are not straightforward since expected effects are limited by the intrinsically fixed character of the underlying lung damage.
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Methodology and baseline characteristics of a randomized controlled trial testing a health care professional and peer-support program for patients with chronic obstructive pulmonary disease: The BREATHE2 study
Hanan Aboumatar,Mohammad Naqibuddin,Joseph Neiman,Jamia Saunders,Samuel Kim,Hina Chaudhry,Emmanuel Garcia-Morales,Nancy Robinson,Marjorie McBurney,Leah Jager,Tokunbo Ajayi,Lee R. Bone,Suna Chung,Bernard Farrell,Hui Joo Jin,John Linnell,Marlene Pirfo,Cynthia S. Rand,Peggy Riley,Carmen Salvaterra,Kai Shea,Jorawar Singh,Robert A. Wise +22 more
TL;DR: A dual strategy for providing support to patients with COPD that incorporates peer and health care professional support is tested and if shown effective, the study offers a program of peer support that can be readily implemented in health care settings.
Journal ArticleDOI
Observational studies assessing the pharmacological treatment of obstructive lung disease: strengths, challenges and considerations for study design.
TL;DR: The features associated with the diagnosis of asthma and chronic obstructive pulmonary disease in the real-world clinical practice setting are described and how observational studies can support RCTs in influencing clinical practice in the field of obstructive lung disease is discussed.
Journal ArticleDOI
Predictive factors for moderate or severe exacerbations in asthma patients receiving outpatient care
Francisco Javier Álvarez Gutiérrez,Marta Ferrer Galván,Juan Francisco Medina Gallardo,Marta Barrera Mancera,Beatriz Romero Romero,Auxiliadora Romero Falcón +5 more
TL;DR: SEs seem to constitute a specific patient "phenotype", in which the sole predictive factor is prior SEs.
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Improving the risk-to-benefit ratio of inhaled corticosteroids through delivery and dose: current progress and future directions.
TL;DR: In this article, the authors give an overview of novel treatment strategies regarding the safety of ICS therapy on the basis of the 3 most recent molecules introduced to our everyday clinical practice -ciclesonide, mometasone furoate, and fluticasone fluroate.
References
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Lung volumes and forced ventilatory flows
TL;DR: Assessing the total lung capacity is indispensable in establishing a restrictive ventilatory defect or in diagnosing abnormal lung distensibility, as may occur in patients …
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Development of the asthma control test: A survey for assessing asthma control
Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
TL;DR: Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.
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Evaluation of Clinical Methods for Rating Dyspnea
TL;DR: The results show that the BDI, MRC scale, and OCD provide significantly related measures of Dyspnea, and the clinical ratings of dyspnea correlate significantly with physiologic parameters of lung function; and breathlessness may be related to the pathophysiology of the specific respiratory disease.
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Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
TL;DR: It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.
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Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
Violaine Giraud,Nicolas Roche +1 more
TL;DR: Misuse of pressurized metered-dose inhalers, which is mainly due to poor coordination, is frequent and associated with poorer asthma control in inhaled corticosteroid-treated asthmatics, highlighting the importance of evaluating inhalation technique and providing appropriate education in all patients.
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