Inhaler mishandling remains common in real life and is associated with reduced disease control
Andrea S. Melani,Marco Bonavia,Vincenzo Cilenti,Cristina Cinti,Marco Lodi,Paola Martucci,Maria Serra,Nicola Scichilone,Piersante Sestini,Maria Aliani,Margherita Neri +10 more
TLDR
In this paper, the authors investigated the prevalence of inhaler mishandling in a large population of experienced patients referring to chest clinics; to analyze the variables associated with misuse and the relationship between inhaler handling and health-care resources use and disease control.About:
This article is published in Respiratory Medicine.The article was published on 2011-06-01 and is currently open access. It has received 681 citations till now. The article focuses on the topics: Dry-powder inhaler & Inhaler.read more
Citations
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Devices for oral and respiratory paediatric medicines: What do healthcare professionals think?
TL;DR: The results show country- and age-dependent usage of devices for oral administration of liquid formulations, with a clear preference for oral droppers and syringes in the neonatal phase and in early infancy, and patient difficulties in correct oral and respiratory device use were identified and potential solutions discussed.
Journal ArticleDOI
Seven Pillars of Small Airways Disease in Asthma and COPD - Supporting Opportunities for Novel Therapies
Omar S. Usmani,MeiLan K. Han,David A. Kaminsky,James C. Hogg,Josephine Hjoberg,Naimish Patel,Megan Hardin,Christina Keen,Stephen I. Rennard,Stephen I. Rennard,François-Xavier Blé,Mary N. Brown +11 more
TL;DR: In this paper, the authors discuss the role of small airway dysfunction in early disease in the airways, along with the identification of novel end points to measure subclinical changes in this region (i.e., those not captured as symptoms or identified through standard FEV1).
Journal ArticleDOI
Impact of holding position during inhalation on drug release from a reservoir-, blister- and capsule-type dry powder inhaler.
Tetsuri Kondo,Toshimori Tanigaki,Haruko Yokoyama,Makoto Hibino,Sakurakao Tajiri,Kenichiro Akazawa,Yasuhiko Yamada,Stanley Morris Cassan +7 more
TL;DR: The position in which the DPI is held may affect drug delivery, especially when using BZH, and significant reductions in drug release were observed while the device was tilted by 30–90°.
Journal ArticleDOI
Using web-based videos to improve inhalation technique in COPD patients requiring hospitalization: A randomized controlled trial.
Wolfram Windisch,Sarah Bettina Schwarz,Friederike Sophie Magnet,Michael Dreher,Claudia Schmoor,Jan Hendrik Storre,Verena Knipel +6 more
TL;DR: Web-based video teaching is capable of reducing inhalation errors, however, compared to personal instruction non-inferiority could not be established due to an unexpectedly high number of patients with persisting inhalations errors despite training.
Journal ArticleDOI
Investigating Cascade Impactor Performance using a Modified 3D Printed Induction Port
TL;DR: This study shows that replacing the USP IP by the mIP can provide additional information in formulation assessment and in in vitro/in vivo correlation, when applied on pMDI formulations.
References
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Robert A. Nathan,Christine A. Sorkness,Mark Kosinski,Michael Schatz,James T.C. Li,Philip Marcus,John J. Murray,T.B. Pendergraft +7 more
TL;DR: Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.
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TL;DR: The results show that the BDI, MRC scale, and OCD provide significantly related measures of Dyspnea, and the clinical ratings of dyspnea correlate significantly with physiologic parameters of lung function; and breathlessness may be related to the pathophysiology of the specific respiratory disease.
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Effect of incorrect use of dry powder inhalers on management of patients with asthma and COPD
Federico Lavorini,Antoine Magnan,Antoine Magnan,Jean Christophe Dubus,Thomas Voshaar,Lorenzo Corbetta,Mariëlle E.A.C. Broeders,Richard Dekhuijzen,Joaquín Sanchis,José Luis Viejo,Peter J. Barnes,Christopher Corrigan,Mark L Levy,Graham K. Crompton +13 more
TL;DR: It is demonstrated that incorrect DPI technique with established DPIs is common among patients with asthma and COPD, and suggests that poor inhalation technique has detrimental consequences for clinical efficacy.
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Misuse of corticosteroid metered-dose inhaler is associated with decreased asthma stability
Violaine Giraud,Nicolas Roche +1 more
TL;DR: Misuse of pressurized metered-dose inhalers, which is mainly due to poor coordination, is frequent and associated with poorer asthma control in inhaled corticosteroid-treated asthmatics, highlighting the importance of evaluating inhalation technique and providing appropriate education in all patients.
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