Journal ArticleDOI
Interventions to enhance testing, linkage to care and treatment uptake for hepatitis C virus infection among people who inject drugs: A systematic review
TLDR
In the direct acting antiviral treatment era, well-designed studies evaluating interventions to enhance a simplified care cascade are crucial in facilitating treatment scale-up.About:
This article is published in International Journal of Drug Policy.The article was published on 2017-09-01. It has received 158 citations till now. The article focuses on the topics: Clinical trial.read more
Citations
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Clinical effectiveness of pharmacy-led versus conventionally delivered antiviral treatment for hepatitis C in patients receiving opioid substitution therapy: a study protocol for a pragmatic cluster randomised trial
TL;DR: This study examines whether a pharmacist-led ‘test & treat’ pathway increases cure rates for HCV and describes a cluster-randomised trial where 60 community pharmacies provide either conventional or pharmacy-led care.
Journal ArticleDOI
Integrating HCV testing with HIV programs improves hepatitis C outcomes in people who inject drugs: A cluster-randomized trial.
Sunil S. Solomon,Sunil S. Solomon,Thomas C. Quinn,Thomas C. Quinn,Suniti Solomon,Allison M. McFall,Aylur K. Srikrishnan,Vinita Verma,Muniratnam S. Kumar,Oliver Laeyendecker,Oliver Laeyendecker,David D. Celentano,Syed H. Iqbal,Santhanam Anand,Canjeevaram K. Vasudevan,Shanmugam Saravanan,David L. Thomas,Kuldeep Singh Sachdeva,Gregory M. Lucas,Shruti H. Mehta +19 more
TL;DR: DeliveringHCV testing to people who inject drugs (PWID) in places where they also have access to HIV prevention and treatment services is an effective way to improve uptake of HCV testing among communities of PWID, providing among the first empirical support for integrating HCVTesting with HIV/harm reduction services.
Journal ArticleDOI
Hepcare Europe - bridging the gap in the treatment of hepatitis C: study protocol.
Davina Swan,Walter Cullen,Juan Macias,Cristiana Oprea,Alistair Story,Julian Surey,Peter Vickerman,John S. Lambert,John S. Lambert +8 more
TL;DR: The Hepcare Europe project is described, a collaboration between five institutions across four member states to develop, implement and evaluate interventions to improve the identification, evaluation and treatment of HCV among PWID.
Journal ArticleDOI
Point-of-care Hepatitis C virus testing and linkage to treatment in an Australian inner-city emergency department.
Jennie Hutton,Joseph Doyle,Rachel Zordan,Tracey J Weiland,A. Cocco,Jessica Howell,S. Iser,J. Snell,S Fry,K. New,R. Sloane,Molly P. Jarman,D. Phan,S. Tran,Alisa Pedrana,Bridget Williams,J. Johnson,S. Glasgow,Alexander J. Thompson +18 more
TL;DR: A history of injecting drug use was identified as the risk factor with highest yield for positive HCV serology, and is suitable as a single screening question, however, linkage to care post ED presentation was low in this marginalised population.
Journal ArticleDOI
Utility of a one-step screening and diagnosis strategy for viremic HCV infection among people who inject drugs in Catalonia.
Verónica Saludes,Adrián Antuori,Cinta Folch,Noemí González,Nuria Ibáñez,Xavier Majó,Joan Colom,Lurdes Matas,Jordi Casabona,Elisa Martró +9 more
TL;DR: The high viremic HCV infection burden among PWID attending HRS, estimated for the first time in Catalonia, suggest that scaling up this one-step screening and diagnosis strategy to the network of harm-reduction services would help to achieve HCV elimination targets set by the World Health Organization.
References
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Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.
Jonathan A C Sterne,Miguel A. Hernán,Barnaby C Reeves,Jelena Savović,Jelena Savović,Nancy D. Berkman,Meera Viswanathan,David Henry,Douglas G. Altman,Mohammed T. Ansari,Isabelle Boutron,James R. Carpenter,An-Wen Chan,Rachel Churchill,Jonathan J Deeks,Asbjørn Hróbjartsson,Jamie J Kirkham,Peter Jüni,Yoon K. Loke,Theresa D Pigott,Craig R Ramsay,Deborah L. Regidor,Hannah R. Rothstein,Lakhbir Sandhu,Pasqualina Santaguida,Holger J. Schünemann,Beverly Shea,Ian Shrier,Peter Tugwell,Lucy Turner,Jeffrey C. Valentine,Hugh Waddington,Elizabeth Waters,George A. Wells,Penny Whiting,Julian P T Higgins +35 more
TL;DR: Risk of Bias In Non-randomised Studies - of Interventions is developed, a new tool for evaluating risk of bias in estimates of the comparative effectiveness of interventions from studies that did not use randomisation to allocate units or clusters of individuals to comparison groups.
Journal ArticleDOI
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: This Explanation and Elaboration document explains the meaning and rationale for each checklist item and includes an example of good reporting and, where possible, references to relevant empirical studies and methodological literature.
Journal ArticleDOI
The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV Infection
Edward M. Gardner,Margaret P. McLees,John F. Steiner,John F. Steiner,Carlos del Rio,William J. Burman +5 more
TL;DR: The spectrum of engagement in care for HIV-infected individuals in the United States is reviewed and this information is applied to help understand the magnitude of the challenges that pooragement in care will pose to test-and-treat strategies for HIV prevention.
Journal ArticleDOI
Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews
Paul K. Nelson,Bradley Mathers,Benjamin C Cowie,Holly Hagan,Don C. Des Jarlais,Danielle Horyniak,Louisa Degenhardt,Louisa Degenhardt +7 more
TL;DR: More IDUs have anti-HCV than HIV infection, and viral hepatitis poses a key challenge to public health, which will inform efforts to prevent and treat HCV and HBV in IDUs.
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