Journal ArticleDOI
Interventions to enhance testing, linkage to care and treatment uptake for hepatitis C virus infection among people who inject drugs: A systematic review
TLDR
In the direct acting antiviral treatment era, well-designed studies evaluating interventions to enhance a simplified care cascade are crucial in facilitating treatment scale-up.About:
This article is published in International Journal of Drug Policy.The article was published on 2017-09-01. It has received 158 citations till now. The article focuses on the topics: Clinical trial.read more
Citations
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Journal ArticleDOI
Performance evaluation of the Hologic Aptima HCV Quant Dx assay for detection of HCV RNA from dried blood spots.
Beth Catlett,Alex Carrera,Mitchell Starr,Tanya L. Applegate,Peter Lowe,Jason Grebely,H. Philip Cunningham +6 more
TL;DR: The data indicates that the Aptima HCV Dx Quant can detect active HCV infection from a DBS sample with good sensitivity and specificity, particularly when using a threshold of ≥1000 IU/mL.
Journal ArticleDOI
Reducing Read Time of Point-of-Care Test Does Not Affect Detection of Hepatitis C Virus and Reduces Need for Reflex RNA.
David Smookler,Aaron Vanderhoff,Mia J. Biondi,Jorge Valencia,Pablo Ryan,Joel Karkada,Rachel Hong,Izza Sattar,Erin Mandel,Martina Gjevori,Julia Casey,David Fletcher,Hemant Shah,Bettina E. Hansen,Bettina E. Hansen,Camelia Capraru,Harry L.A. Janssen,Jeffrey V. Lazarus,Jordan J. Feld +18 more
TL;DR: The wait time for the OraQuick HCV Rapid antibody POC blood test can be reduced from 20 min to 5 min and continue to reliably identify patients with HCV infection, which could increase high-throughput screening, reduce loss to follow up, and reduce the need for reflex HCV RNA testing.
Book ChapterDOI
HIV and the liver.
TL;DR: Among individuals with HIV infection, liver disease remains an important cause of morbidity and mortality, even with the availability of agents that cure hepatitis C infection and suppress hepatitis B replication.
Journal ArticleDOI
Evaluation of a hepatitis C virus core antigen assay from venepuncture and dried blood spot collected samples: A cohort study
Beth Catlett,F. Lamoury,Sahar Bajis,Behzad Hajarizadeh,Danica Martinez,Yasmin Mowat,Philip H Cunningham,Brendan Jacka,Gavin Cloherty,Philippa Marks,Gregory J. Dore,Jason Grebely,Tanya L. Applegate +12 more
TL;DR: Data indicate that the detection of HCVcAg is a useful tool for determining active HCV infection; to facilitate enhanced testing, linkage to care and treatment particularly when testing plasma samples are collected by venepuncture.
Journal ArticleDOI
Integrating Care for Diabetes and Hypertension with HIV Care in Sub-Saharan Africa: A Scoping Review
Geoff McCombe,Jayleigh Lim,Marie Claire Van Hout,Jeffrey V. Lazarus,Max Bachmann,Shabbar Jaffar,Anu Garrib,Kaushik Ramaiya,Nelson K. Sewankambo,Sayoki Mfinanga,Walter Cullen +10 more
TL;DR: The review confirms that integrated HIV and NCD care services is by-and-large feasible, being both clinically effective and cost-effective.
References
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Journal ArticleDOI
The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: An Explanation and Elaboration of the PRISMA Statement is presented and updated guidelines for the reporting of systematic reviews and meta-analyses are presented.
Journal ArticleDOI
ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions.
Jonathan A C Sterne,Miguel A. Hernán,Barnaby C Reeves,Jelena Savović,Jelena Savović,Nancy D. Berkman,Meera Viswanathan,David Henry,Douglas G. Altman,Mohammed T. Ansari,Isabelle Boutron,James R. Carpenter,An-Wen Chan,Rachel Churchill,Jonathan J Deeks,Asbjørn Hróbjartsson,Jamie J Kirkham,Peter Jüni,Yoon K. Loke,Theresa D Pigott,Craig R Ramsay,Deborah L. Regidor,Hannah R. Rothstein,Lakhbir Sandhu,Pasqualina Santaguida,Holger J. Schünemann,Beverly Shea,Ian Shrier,Peter Tugwell,Lucy Turner,Jeffrey C. Valentine,Hugh Waddington,Elizabeth Waters,George A. Wells,Penny Whiting,Julian P T Higgins +35 more
TL;DR: Risk of Bias In Non-randomised Studies - of Interventions is developed, a new tool for evaluating risk of bias in estimates of the comparative effectiveness of interventions from studies that did not use randomisation to allocate units or clusters of individuals to comparison groups.
Journal ArticleDOI
The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration
Alessandro Liberati,Douglas G. Altman,Jennifer Tetzlaff,Cynthia D. Mulrow,Peter C Gøtzsche,John P. A. Ioannidis,Mike Clarke,Mike Clarke,Philip J. Devereaux,Jos Kleijnen,David Moher +10 more
TL;DR: This Explanation and Elaboration document explains the meaning and rationale for each checklist item and includes an example of good reporting and, where possible, references to relevant empirical studies and methodological literature.
Journal ArticleDOI
The Spectrum of Engagement in HIV Care and its Relevance to Test-and-Treat Strategies for Prevention of HIV Infection
Edward M. Gardner,Margaret P. McLees,John F. Steiner,John F. Steiner,Carlos del Rio,William J. Burman +5 more
TL;DR: The spectrum of engagement in care for HIV-infected individuals in the United States is reviewed and this information is applied to help understand the magnitude of the challenges that pooragement in care will pose to test-and-treat strategies for HIV prevention.
Journal ArticleDOI
Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews
Paul K. Nelson,Bradley Mathers,Benjamin C Cowie,Holly Hagan,Don C. Des Jarlais,Danielle Horyniak,Louisa Degenhardt,Louisa Degenhardt +7 more
TL;DR: More IDUs have anti-HCV than HIV infection, and viral hepatitis poses a key challenge to public health, which will inform efforts to prevent and treat HCV and HBV in IDUs.
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