Iron management in chronic kidney disease: conclusions from a “Kidney Disease: Improving Global Outcomes” (KDIGO) Controversies Conference
Iain C. Macdougall,Andreas J. Bircher,Kai-Uwe Eckardt,Gregorio T. Obrador,Carol A. Pollock,Carol A. Pollock,Peter Stenvinkel,Dorine W. Swinkels,Christoph Wanner,Günter Weiss,Glenn M. Chertow,John W. Adamson,Tadao Akizawa,Stefan D. Anker,Michael Auerbach,Peter Bárány,Anatole Besarab,Sunil Bhandari,Ioav Cabantchik,Alan J. Collins,Daniel W. Coyne,Angel L.M. de Francisco,Steven Fishbane,Carlo A. J. M. Gaillard,Tomas Ganz,David Goldsmith,Chaim Hershko,Ewa A. Jankowska,Kirsten L. Johansen,Kamyar Kalantar-Zadeh,Philip A. Kalra,Bertram L. Kasiske,Francesco Locatelli,Jolanta Malyszko,Gert Mayer,Lawrence P. McMahon,Ashraf Mikhail,Elizabeta Nemeth,Amy Barton Pai,Patrick S. Parfrey,Roberto Pecoits-Filho,Simon D. Roger,Guy Rostoker,Jacques Rottembourg,Ajay K. Singh,Itzchak Slotki,Bruce Spinowitz,Der Cherng Tarng,Francesca Tentori,Jorge E. Toblli,Yusuke Tsukamoto,Nosratola D. Vaziri,Wolfgang C. Winkelmayer,David C. Wheeler,Elena Zakharova +54 more
TLDR
An expert group was convened to assess the benefits and risks of parenteral iron, and to provide strategies for its optimal use while mitigating the risk for acute reactions and other adverse effects.About:
This article is published in Kidney International.The article was published on 2019-05-01 and is currently open access. It has received 350 citations till now. The article focuses on the topics: Kidney disease & Guideline.read more
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Targeting Hypoxia-Inducible Factors for the Treatment of Anemia in Chronic Kidney Disease Patients
TL;DR: Results from clinical studies of a number of HIF prolyl hydroxylase inhibitors are increasingly available and provide support for the continued evaluation of the risk-benefit ratio of this novel therapeutic approach to the treatment of anemia in CKD.
Journal ArticleDOI
KDIGO 2021 Clinical Practice Guideline for the Management of Blood Pressure in Chronic Kidney Disease
Alfred K. Cheung,Tara I. Chang,William C. Cushman,Susan L. Furth,Fan Fan Hou,Joachim H. Ix,Gregory A. Knoll,Paul Muntner,Roberto Pecoits-Filho,Mark J. Sarnak,Sheldon W. Tobe,Charles R.V. Tomson,Johannes F.E. Mann +12 more
Journal ArticleDOI
Intravenous Iron in Patients Undergoing Maintenance Hemodialysis.
Iain C. Macdougall,Claire White,Stefan Anker,Sunil Bhandari,Ken Farrington,Philip A. Kalra,John J.V. McMurray,Heather M. Murray,Charles R.V. Tomson,David C. Wheeler,Christopher G. Winearls,Ian Ford +11 more
TL;DR: Among patients undergoing hemodialysis, a high‐dose intravenous iron regimen administered proactively was superior to a low‐dose regimen administered reactively and resulted in lower doses of erythropoiesis‐stimulating agent being administered.
Journal ArticleDOI
Overview of iron metabolism in health and disease
Som Dev,Jodie L. Babitt +1 more
TL;DR: An overview of the essential role of iron in biology, the regulation of systemic and cellular iron homeostasis, how imbalances in ironHomeostasis contribute to disease, and the implications for chronic kidney disease patients is provided.
Journal ArticleDOI
Iron deficiency anaemia revisited
TL;DR: This review provides recent updates and guidance on the diagnosis and management of iron deficiency anaemia in multiple clinical settings.
References
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2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC.
Piotr Ponikowski,Adriaan A. Voors,Stefan D. Anker,Héctor Bueno,John G.F. Cleland,Andrew J.S. Coats,Volkmar Falk,José Ramón González-Juanatey,Veli-Pekka Harjola,Ewa A. Jankowska,Mariell Jessup,Cecilia Linde,Petros Nihoyannopoulos,John Parissis,Burkert Pieske,Jillian P. Riley,Giuseppe M.C. Rosano,Luis M. Ruilope,Frank Ruschitzka,Frans H. Rutten,Peter van der Meer,Gerasimos Filippatos,John J.V. McMurray,Victor Aboyans,Stephan Achenbach,Stefan Agewall,Nawwar Al-Attar,John Atherton,Johann Bauersachs,A. John Camm,Scipione Carerj,Claudio Ceconi,Antonio Coca,Perry M. Elliott,Çetin Erol,Justin A. Ezekowitz,Covadonga Fernández-Golfín,Donna Fitzsimons,Marco Guazzi,Maxime Guenoun,Gerd Hasenfuss,Gerhard Hindricks,Arno W. Hoes,Bernard Iung,Tiny Jaarsma,Paulus Kirchhof,Juhani Knuuti,Philippe Kolh,Stavros Konstantinides,Mitja Lainscak,Patrizio Lancellotti,Gregory Y.H. Lip,Francesco Maisano,Christian Mueller,Mark C. Petrie,Massimo F Piepoli,Silvia G. Priori,Adam Torbicki,Hiroyuki Tsutsui,Dirk J. van Veldhuisen,Stephan Windecker,Clyde W. Yancy,José Luis Zamorano +62 more
TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)
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The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators.
Bertram Pitt,Faiez Zannad,Willem J. Remme,Robert J. Cody,Alain Castaigne,Alfonso Perez,Jolie Palensky,Janet Wittes +7 more
TL;DR: Blockade of aldosterone receptors by spironolactone, in addition to standard therapy, substantially reduces the risk of both morbidity and death among patients with severe heart failure.
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Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.
Bernard Zinman,Christoph Wanner,John M. Lachin,David Fitchett,Erich Bluhmki,Stefan Hantel,Michaela Mattheus,Theresa Devins,Odd Erik Johansen,Hans-Juergen Woerle,Uli C. Broedl,Silvio E. Inzucchi +11 more
TL;DR: Patients with type 2 diabetes at high risk for cardiovascular events who received empagliflozin, as compared with placebo, had a lower rate of the primary composite cardiovascular outcome and of death from any cause when the study drug was added to standard care.
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2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Piotr Ponikowski,Adriaan A. Voors,Stefan D. Anker,Héctor Bueno,John G.F. Cleland,Andrew J.S. Coats,Volkmar Falk,José Ramón González-Juanatey,Veli-Pekka Harjola,Ewa A. Jankowska,Mariell Jessup,Cecilia Linde,Petros Nihoyannopoulos,John Parissis,Burkert Pieske,Jillian P. Riley,Giuseppe M.C. Rosano,Luis M. Ruilope,Frank Ruschitzka,Frans H. Rutten,Peter van der Meer +20 more
TL;DR: ACCF/AHAIAI: angiotensin-converting enzyme inhibitor as discussed by the authors, angio-catabolizing enzyme inhibitor inhibitor inhibitor (ACS inhibitor) is a drug that is used to prevent atrial fibrillation.
Journal ArticleDOI
2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
Piotr Ponikowski,Adriaan A. Voors,Stefan D. Anker,Héctor Bueno,John G.F. Cleland,Andrew J.S. Coats,Volkmar Falk,José Ramón González-Juanatey,Veli-Pekka Harjola,Ewa A. Jankowska,Mariell Jessup,Cecilia Linde,Petros Nihoyannopoulos,John Parissis,Burkert Pieske,Jillian P. Riley,Giuseppe M.C. Rosano,Luis M. Ruilope,Frank Ruschitzka,Frans H. Rutten,Peter van der Meer +20 more
TL;DR: Authors/Task Force Members: Piotr Ponikowski* (Chairperson) (Poland), Adriaan A. Voors* (Co-Chair person) (The Netherlands), Stefan D. Anker (Germany), Héctor Bueno (Spain), John G. F. Cleland (UK), Andrew J. S. Coats (UK)
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