Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research
Paul A. Brogan,Amitabha Bose,David Burgner,D. Shingadia,Robert Tulloh,Colin Michie,Nigel Klein,Robert Booy,Michael Levin,M J Dillon +9 more
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TLDR
A clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date is proposed, and areas of practice where evidence is anecdotal or based on retrospective data are highlighted.Abstract:
This article proposes a clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date, and highlights areas of practice where evidence is anecdotal or based on retrospective data. Future research as proposed by the London Kawasaki Disease Research Group is outlined, and clinicians are invited to prospectively enrol their suspected cases into this collaborative research project.read more
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Book ChapterDOI
Common Childhood Vasculitis
TL;DR: Though conventional coronary angiography remains the gold standard diagnostic modality, Doppler color echocardiography allows non-invasively the detection and the monitoring of coronary artery lesions.
Journal Article
A case report of kawasaki’s disease in a 17 year old woman
TL;DR: Partial Kawasaki’s disease was suspected due to the patient having a high grade fever of over five days duration with no obvious cause, and three of the five classical criteria namely sore, cracked lips; desquamating rash of the extremities and polymorphous exanthema.
Reports of children with Kawasaki disease hospitalized in pediatric
TL;DR: The report shows a higher prevalence of atypical Kawasaki disease in these two hospitals compared to other areas and emphasizes the importance of accurate clinical examinations during early stages which in turn will prevent future complications.
Journal ArticleDOI
Ioning out the diagnosis in chronic diarrhoea
TL;DR: Investigations were ordered: blood count, renal function, serum IgA and endomesial antibodies, and radioallergosorbent tests (RAST, negative), and an oesophageal pH study was also organised.
Journal ArticleDOI
Kawasaki-Syndrom
TL;DR: The Kawasaki-Syndrom (KS) as discussed by the authors is a klare Erkrankung unbekannter Ursache and betrifft hauptsachlich Kinder unter 5 years.
References
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Journal Article
Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children
Journal ArticleDOI
In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
Valery Combes,Anne Christine Simon,Georges E. Grau,D. Arnoux,Laurence Camoin,Florence Sabatier,Murielle Mutin,Marielle Sanmarco,José Sampol,Françoise Dignat-George +9 more
TL;DR: Examination of morphological, immunological, and functional characteristics of MPs derived from human umbilical vein endothelial cells stimulated by TNF provides evidence that endothelial-derived MPs are detectable in normal human blood and are increased in patients with a coagulation abnormality characterized by the presence of lupus anticoagulant.
Journal ArticleDOI
The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment.
TL;DR: The incidence of CAA both at 30 and 60 days was significantly lower in low-IVig than in ASA and in high-IVIG than in low -IVIG groups, but this was noted at 30 days and not at 60 days.
Journal ArticleDOI
Kawasaki Disease: Effect of Treatment on Coronary Artery Involvement
TL;DR: The findings suggest that the steroid might act adversely to cause a progression of coronary lesions of the disease, and aspirin might act as the effective means for prevention of sudden death due to Kawasaki disease.