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Open AccessJournal ArticleDOI

Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research

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TLDR
A clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date is proposed, and areas of practice where evidence is anecdotal or based on retrospective data are highlighted.
Abstract
This article proposes a clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date, and highlights areas of practice where evidence is anecdotal or based on retrospective data. Future research as proposed by the London Kawasaki Disease Research Group is outlined, and clinicians are invited to prospectively enrol their suspected cases into this collaborative research project.

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Book ChapterDOI

Kawasaki Disease in a Tertiary Pediatric Referral Center in Athens, Greece and Review of the Literature

TL;DR: This disease has become the leading cause of acquired heart disease among children in the developed world, with coronary artery aneurysms occurring in up to 25% of untreated cases.
Journal ArticleDOI

An atypical case of Kawasaki disease presenting with cholestatic jaundice

TL;DR: Sri Lanka Journal of Child Health, 2015; 44 (1): 58-60 DOI: http://dx.doi.org/10.4038/sljch.v44i1.7965
Journal ArticleDOI

A 2 year old child with rash and fever

TL;DR: Elisabeth first became unwell during the evening of her 2nd birthday when she woke with a temperature of 38.9°C and during the next two days her fever, lethargy, and irritability persisted despite regular paracetamol.
References
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Kawasaki Disease

Hiroshisa Kato, +1 more
Journal ArticleDOI

In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant

TL;DR: Examination of morphological, immunological, and functional characteristics of MPs derived from human umbilical vein endothelial cells stimulated by TNF provides evidence that endothelial-derived MPs are detectable in normal human blood and are increased in patients with a coagulation abnormality characterized by the presence of lupus anticoagulant.
Journal ArticleDOI

The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment.

TL;DR: The incidence of CAA both at 30 and 60 days was significantly lower in low-IVig than in ASA and in high-IVIG than in low -IVIG groups, but this was noted at 30 days and not at 60 days.
Journal ArticleDOI

Kawasaki Disease: Effect of Treatment on Coronary Artery Involvement

TL;DR: The findings suggest that the steroid might act adversely to cause a progression of coronary lesions of the disease, and aspirin might act as the effective means for prevention of sudden death due to Kawasaki disease.
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