Kawasaki disease: an evidence based approach to diagnosis, treatment, and proposals for future research
Paul A. Brogan,Amitabha Bose,David Burgner,D. Shingadia,Robert Tulloh,Colin Michie,Nigel Klein,Robert Booy,Michael Levin,M J Dillon +9 more
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TLDR
A clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date is proposed, and areas of practice where evidence is anecdotal or based on retrospective data are highlighted.Abstract:
This article proposes a clinical guideline for the diagnosis and treatment of Kawasaki disease in the UK based on the best available evidence to date, and highlights areas of practice where evidence is anecdotal or based on retrospective data. Future research as proposed by the London Kawasaki Disease Research Group is outlined, and clinicians are invited to prospectively enrol their suspected cases into this collaborative research project.read more
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Infarto Agudo do Miocárdio em Adolescente Secundário à Trombose de Aneurisma Coronariano Acute Myocardial Infarction in Adolescent Secondary to Coronary Aneurysm Thrombosis
TL;DR: O aneurisma de arteria coronaria e uma doenca geralmente descoberta de forma acidental ja que a maioria dos pacientses permanece assintomatica, raros pacientes podem apresentar complicacoes locais do aneurism.
Journal ArticleDOI
Relapse of nephrotic syndrome triggered by Kawasaki disease.
TL;DR: The first case of NS relapse due to Kawasaki disease (KD) is reported in an 8-year-old boy, whose NS relapsed due to KD, and it is necessary to recognize that KD can trigger relapse of MCNS.
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A case of gastroduodenal ulcer complicating Kawasaki disease
TL;DR: A 3-year-old boy who presented with hematemesis and gastroduodenal ulcer complicating KD is reported, and the gastrointestinal manifestations have not been reported as complications of KD.
Inmunoglobulina intravenosa en dermatosis infantiles
TL;DR: Current dermatologic indications of IV Ig, although diverse, only are definite for Kawasaki disease, dermatomyositis and erythema multiforme major, and other indications derive from non randomized trials or case reports.
References
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Journal Article
Acute febrile mucocutaneous syndrome with lymphoid involvement with specific desquamation of the fingers and toes in children
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In vitro generation of endothelial microparticles and possible prothrombotic activity in patients with lupus anticoagulant
Valery Combes,Anne Christine Simon,Georges E. Grau,D. Arnoux,Laurence Camoin,Florence Sabatier,Murielle Mutin,Marielle Sanmarco,José Sampol,Françoise Dignat-George +9 more
TL;DR: Examination of morphological, immunological, and functional characteristics of MPs derived from human umbilical vein endothelial cells stimulated by TNF provides evidence that endothelial-derived MPs are detectable in normal human blood and are increased in patients with a coagulation abnormality characterized by the presence of lupus anticoagulant.
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The prevention of coronary artery aneurysm in Kawasaki disease: a meta-analysis on the efficacy of aspirin and immunoglobulin treatment.
TL;DR: The incidence of CAA both at 30 and 60 days was significantly lower in low-IVig than in ASA and in high-IVIG than in low -IVIG groups, but this was noted at 30 days and not at 60 days.
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Kawasaki Disease: Effect of Treatment on Coronary Artery Involvement
TL;DR: The findings suggest that the steroid might act adversely to cause a progression of coronary lesions of the disease, and aspirin might act as the effective means for prevention of sudden death due to Kawasaki disease.