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Journal ArticleDOI

Lipid phase transitions and membrane function

Peter Overath, +2 more
- 01 Aug 1976 - 
- Vol. 1, Iss: 3, pp 186-189
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TLDR
An attempt to understand the mechanism by which a structural transition in the membrane lipids of a bacterial cytoplasmic membrane affects the transport functions of the membrane.
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This article is published in Trends in Biochemical Sciences.The article was published on 1976-08-01. It has received 38 citations till now. The article focuses on the topics: Membrane fluidity & Elasticity of cell membranes.

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Citations
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Journal ArticleDOI

5-aminolevulinic acid, but not 5-aminolevulinic acid esters, is transported into adenocarcinoma cells by system BETA transporters.

TL;DR: 5-ALA, but not 5- ALA methyl ester, was found to inhibit cellular uptake of [3H]-GABA and [14C]-β-alanine, and is transported by β-amino acid and GABA carriers in this cell line.
Journal ArticleDOI

Mechanistic interpretation of the influence of lipid phase transitions on transport functions.

L Thilo, +2 more
- 05 Apr 1977 - 
TL;DR: In an attempt to understand the mechanism by which a structural change of membrane lipids affects transport functions, the temperature dependence of transport rate has been measured to below the low temperature end of the fluid in equilibrium ordered phase transition of the membrane Lipids.
Journal ArticleDOI

Microvillus membrane vesicles from pig small intestine Purity and lipid composition

TL;DR: The purity of the membrane vesicles were established by measuring the activity of marker enzymes and the RNA and DNA content, and the lipid composition was established and the membranes were found free of contamination by other subcellular membrane fragments, except for a minor contamination with basolateral plasma membranes.
Journal ArticleDOI

Effect of the phase transition on the transbilayer movement of dimyristoyl phosphatidylcholine in unilamellar vesicles.

TL;DR: The rate of transbilayer movement of dimyristoyl phosphatidylcholine shows a distinct maximum (half-time 4 h) in the temperature range at which the hydrocarbon phase transition occurs.
References
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Journal ArticleDOI

Lipid bilayer structure in the membrane of Mycoplasma laidlawii

TL;DR: X-ray diffraction patterns from intact, isolated Mycoplasma laidlawii membranes at temperatures above and below the thermal phase transition of the membrane lipids reveal important features of the molecular structure of the membranes.
Journal ArticleDOI

The effect of membrane lipid unsaturation on glycoside transport.

TL;DR: The data suggest that the membrane may exist in two physical states, one above and the other below a transition point determined by the composition of the lipid phase.
Journal ArticleDOI

Temperature “breaks” in Arrhenius plots: A thermodynamic consequence of a phase change

TL;DR: Temperature “breaks” in Arrhenius plots of biological data are real and can be explained as a consequence of a phase change in the system.
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