Journal ArticleDOI
Lung cancer-A global perspective.
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TLDR
There is a global variation in lung cancer biology with EGFR mutations being more common in Asian patients, while Kras mutation is moreCommon in Caucasians.Abstract:
Lung cancer is the leading cause of cancer deaths worldwide. While tobacco exposure is responsible for the majority of lung cancers, the incidence of lung cancer in never smokers, especially Asian women, is increasing. There is a global variation in lung cancer biology with EGFR mutations being more common in Asian patients, while Kras mutation is more common in Caucasians. This review will focus on the global variations in lung cancer and its treatment.read more
Citations
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Lung Cancer in Never Smokers - Different Disease
TL;DR: Current knowledge of lung cancers arising in never smokers versus smokers is summarized, suggesting that they are separate entities.
Journal ArticleDOI
Emerging trends in the novel drug delivery approaches for the treatment of lung cancer
Parvarish Sharma,Meenu Mehta,Daljeet Singh Dhanjal,Simran Kaur,Gaurav Gupta,Harjeet Singh,Lakshmi Thangavelu,Shanmugam Rajeshkumar,Murtaza M. Tambuwala,Hamid A. Bakshi,Dinesh Kumar Chellappan,Kamal Dua,Saurabh Satija +12 more
TL;DR: In this review, various modes of nano drug delivery options like liposomes, dendrimers, quantum dots, carbon nanotubes and metallic nanoparticles have been discussed.
Journal ArticleDOI
Epidemiology of lung cancer in China: Epidemiology of lung cancer in China
Maomao Cao,Wanqing Chen +1 more
TL;DR: Behavioral intervention, such as smoking cessation and screening, could effectively reduce lung cancer incidence and mortality in China.
Journal ArticleDOI
The health and social implications of household air pollution and respiratory diseases
Suzanne M. Simkovich,Dina Goodman,Christian Roa,Mary E. Crocker,Mary E. Crocker,Gonzalo Gianella,Bruce Kirenga,Robert A. Wise,William Checkley +8 more
TL;DR: Clinicians should be aware that patients with current or past HAP exposure are at increased risk for respiratory diseases or malignancies and may want to consider earlier screening in this population, and better environmental exposure monitoring is critical.
Journal ArticleDOI
Hsa_circ_0043265 Suppresses Proliferation, Metastasis, EMT and Promotes Apoptosis in Non-Small Cell Lung Cancer Through miR-25-3p/FOXP2 Pathway.
TL;DR: It is shown that hsa_circ_0043265 could be a potential biomarker for early diagnosis of NSCLC and its overexpression inhibited the proliferation, migration, invasion and EMT process, while improved the apoptosis ofNSCLC cells.
References
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Lindsey A. Torre,Freddie Bray,Rebecca L. Siegel,Jacques Ferlay,Joannie Lortet-Tieulent,Ahmedin Jemal +5 more
TL;DR: A substantial portion of cancer cases and deaths could be prevented by broadly applying effective prevention measures, such as tobacco control, vaccination, and the use of early detection tests.
Journal ArticleDOI
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TL;DR: Screening with the use of low-dose CT reduces mortality from lung cancer, as compared with the radiography group, and the rate of death from any cause was reduced.
Harrison's principles of internal medicine
TL;DR: Harrison's principles of internal medicine is a treatise on the foundations of modern medicine and its application in the field of medicine.
Journal ArticleDOI
The Global Burden of Cancer 2013
Christina Fitzmaurice,Christina Fitzmaurice,Daniel Dicker,Daniel Dicker,Amanda W Pain,Hannah Hamavid,Maziar Moradi-Lakeh,Michael F. MacIntyre,Michael F. MacIntyre,Christine Allen,Gillian M. Hansen,Rachel Woodbrook,Charles D.A. Wolfe,Randah R. Hamadeh,Ami R. Moore,A. Werdecker,Bradford D. Gessner,Braden Te Ao,Brian J. McMahon,Chante Karimkhani,Chuanhua Yu,Graham S Cooke,David C. Schwebel,David O. Carpenter,David M. Pereira,Denis Nash,Dhruv S. Kazi,Diego De Leo,Dietrich Plass,Kingsley N. Ukwaja,George D. Thurston,Kim Yun Jin,Edgar P. Simard,Edward J Mills,Eun-Kee Park,Ferrán Catalá-López,Gabrielle deVeber,Carolyn C. Gotay,Gulfaraz Khan,H. Dean Hosgood,Itamar S. Santos,Janet L Leasher,Jasvinder A. Singh,James Leigh,Jost B. Jonas,Juan R. Sanabria,Justin Beardsley,Justin Beardsley,Kathryn H. Jacobsen,Ken Takahashi,Richard C. Franklin,Luca Ronfani,Marcella Montico,Luigi Naldi,Marcello Tonelli,Johanna M. Geleijnse,Max Petzold,Mark G. Shrime,Mark G. Shrime,Mustafa Z. Younis,Naohiro Yonemoto,Nicholas J K Breitborde,Paul S. F. Yip,Farshad Pourmalek,Paulo A. Lotufo,Alireza Esteghamati,Graeme J. Hankey,Raghib Ali,Raimundas Lunevicius,Reza Malekzadeh,Robert P. Dellavalle,Robert G. Weintraub,Robert G. Weintraub,Robyn M. Lucas,Robyn M. Lucas,Roderick J Hay,David Rojas-Rueda,Ronny Westerman,Sadaf G. Sepanlou,Sandra Nolte,Scott B. Patten,Scott Weichenthal,Semaw Ferede Abera,Seyed-Mohammad Fereshtehnejad,Ivy Shiue,Tim Driscoll,Tim Driscoll,Tommi J. Vasankari,Ubai Alsharif,Vafa Rahimi-Movaghar,Vasiliy Victorovich Vlassov,W. S. Marcenes,Wubegzier Mekonnen,Yohannes Adama Melaku,Yuichiro Yano,Al Artaman,Ismael Campos,Jennifer H MacLachlan,Ulrich O Mueller,Daniel Kim,Matias Trillini,Babak Eshrati,Hywel C Williams,Kenji Shibuya,Rakhi Dandona,Kinnari S. Murthy,Benjamin C Cowie,Azmeraw T. Amare,Carl Abelardo T. Antonio,Carlos A Castañeda-Orjuela,Coen H. Van Gool,Francesco Saverio Violante,In-Hwan Oh,Kedede Deribe,Kjetil Søreide,Kjetil Søreide,Luke D. Knibbs,Luke D. Knibbs,Maia Kereselidze,Mark Green,Rosario Cardenas,Nobhojit Roy,Taavi Tillmann,Yongmei Li,Hans Krueger,Lorenzo Monasta,Subhojit Dey,Sara Sheikhbahaei,Nima Hafezi-Nejad,G Anil Kumar,Chandrashekhar T Sreeramareddy,Lalit Dandona,Haidong Wang,Haidong Wang,Stein Emil Vollset,Ali Mokdad,Ali Mokdad,Joshua A. Salomon,Rafael Lozano,Theo Vos,Mohammad H. Forouzanfar,Alan D. Lopez,Christopher J L Murray,Mohsen Naghavi +143 more
TL;DR: To estimate mortality, incidence, years lived with disability, years of life lost, and disability-adjusted life-years for 28 cancers in 188 countries by sex from 1990 to 2013, the general methodology of the Global Burden of Disease 2013 study was used.