Journal ArticleDOI
Macrophages and microglia in the nervous system
V. Hugh Perry,Siamon Gordon +1 more
Reads0
Chats0
TLDR
The possible functions of resident and recruited macrophages in the developing and adult nervous system are reviewed and what contribution these cells might make to repair mechanisms in the central and peripheral nervous systems are examined.About:
This article is published in Trends in Neurosciences.The article was published on 1988-01-01. It has received 745 citations till now. The article focuses on the topics: Microglia & Nervous system.read more
Citations
More filters
Journal ArticleDOI
The cranial meninges: anatomic considerations.
Rona Woldenberg Greenberg,Elizabeth L. Lane,Elizabeth L. Lane,Jay Cinnamon,Jay Cinnamon,Peter Farmer,Peter Farmer,Roger A. Hyman,Roger A. Hyman +8 more
TL;DR: A thorough discussion of the protective covering of the brain including the dura, arachnoid, and pia is provided on both gross and microscopic levels, with an attempt to include issues of clinical relevance.
Journal ArticleDOI
Physiological basis for neuroimmunomodulation.
Pierre J. Neveu,M. Le Moal +1 more
TL;DR: The immunomodulating role of neurotransmitters and neuropeptides and the possible endocrine functions of lymphocytes are described and it is suggested that a complete regulatory loop between immune and neuro‐endocrine systems exists.
Journal ArticleDOI
Haemopoietic biglycan produced by brain cells stimulates growth of microglial cells.
Aiko Kikuchi,Hiroshi Tomoyasu,Isao Kido,Kazuhiro Takahashi,Akio Tanaka,Ikuya Nonaka,Noboru Iwakami,Isao Kamo +7 more
TL;DR: Results suggest that the haemopoietic biglycan plays an important role in generating brain-specific circumstances for development of microglial/monocytic cells in the brain.
Journal ArticleDOI
Cellular repair strategies for spinal cord injury.
TL;DR: Although the progression of cell therapies from laboratory to clinical implementation has been slow, human SCI safety and efficacy trials involving several cell types within the US appear to be close at hand.
Statement of Originality
TL;DR: In this article, As'ari et al. investigated the effectiveness of predicting strategy in teaching reading comprehension on narrative text of the eighth grade students of Islamic Boarding School Daar Al-Ilmi Kota Serang.
References
More filters
Book
Handbook of experimental immunology
TL;DR: This document describes the development and application of various methods for immunologic studies using monoclonal antibodies, a type of antibody, and some of the methods used in these studies are currently in use.
Journal ArticleDOI
Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy.
Scott Koenig,Howard E. Gendelman,Jan M. Orenstein,Mauro C. Dal Canto,Gholam H. Pezeshkpour,Margaret Yungbluth,Frank Janotta,Allen J. Aksamit,Malcolm A. Martin,Anthony S. Fauci +9 more
TL;DR: The identity of an important cell type that supports replication of the AIDS retrovirus in brain tissue was determined in two affected individuals and these cells were mononucleated and multinucleated macrophages that actively synthesized viral RNA and produced progeny virions in the brains of the patients.
Journal ArticleDOI
F4/80, a monoclonal antibody directed specifically against the mouse macrophage
Jonathan M. Austyn,Siamon Gordon +1 more
TL;DR: Immunoprecipitation experiments demonstrated that the antigen F4/80 is part of a component of Mr 160000 which is synthesized by the MΦ and, at least in part, exposed on the cell surface.
Journal ArticleDOI
The AIDS dementia complex: II. Neuropathology
TL;DR: The AIDS dementia complex is established as a distinct clinical and pathological entity and, together with accumulating virological evidence, suggests that it is caused by direct LAV/HTLV‐III brain infection.