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Journal ArticleDOI

Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury.

David R. Janero
- 01 Jan 1990 - 
- Vol. 9, Iss: 6, pp 515-540
TLDR
The conclusion is reached that MDA determination and the TBA test can offer, at best, a narrow and somewhat empirical window on the complex process of lipid peroxidation.
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This article is published in Free Radical Biology and Medicine.The article was published on 1990-01-01. It has received 2540 citations till now. The article focuses on the topics: Lipid peroxidation & TBARS.

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Citations
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Journal ArticleDOI

Improving the thiobarbituric acid-reactive-substances assay for estimating lipid peroxidation in plant tissues containing anthocyanin and other interfering compounds

TL;DR: In this paper, a modified version of the TBARS method was proposed for assessing the presence of malondialdehyde (MDA) and other non-MDA compounds absorbing at 532 nm.
Journal ArticleDOI

The role of lipid peroxidation and antioxidants in oxidative modification of LDL.

TL;DR: A comprehensive survey on the compositional properties of LDL relevant for its susceptibility to oxidation, on the mechanism and kinetics of LDL oxidation, and on the chemical and physico-chemical properties of HDL oxidized by exposure to copper ions is provided.
Journal ArticleDOI

Environmentally induced oxidative stress in aquatic animals

TL;DR: The general processes responsible for ROS generation in aquatic animals are described and the identification of its general characteristics and mechanisms responsible for adaptation to the stress have been discussed.
Journal ArticleDOI

Antimicrobial activity of metals: mechanisms, molecular targets and applications

TL;DR: The chemical and toxicological principles that underlie the antimicrobial activity of metals are described and the preferences of metal atoms for specific microbial targets are discussed.
Journal ArticleDOI

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions.

TL;DR: The effects of tea and green tea catechins on biomarker of oxidative stress, especially oxidative DNA damage, appear very promising in animal models, but data on biomarkers of in vivo oxidative stress in humans are limited.
References
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Journal ArticleDOI

Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction

TL;DR: Using this method, the liped peroxide level in the liver of rats suffering from carbon tetrachloride intoxication was investigated and was in good agreement with previously reported data obtained by measuring diene content.
Journal ArticleDOI

The thiobarbituric acid assay of sialic acids.

TL;DR: This chapter discusses the different aspects of thiobarbituric acid assay of sialic acid, which is suitable for measuring the release of bound sialoic acid by sialidase and hydrolysis of sIALic acid-containing material must be carried out for the measurement of total sialsic acids.
Journal ArticleDOI

Determination of malonaldehyde precursor in tissues by thiobarbituric acid test

TL;DR: It was concluded that the deproteinization of homogenate prior to coloration is not needed, but double wavelength measurement is necessary to avoid interference and the reaction should be performed with phosphoric acid at a definite pH near 2.0.
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