Journal ArticleDOI
Metabolite Profile and Bioactivity of Musa X Paradisiaca L. Flower Extracts
TLDR
The activities of the flower extracts against the enzymes suggest that they may have beneficial effects in controlling diseases, and the chemical constituents present in the methanol extracts were profiled following GC-MS based metabolomics approach.Abstract:
The flower extracts of two cultivated varieties of Musa X paradisiaca viz. Kanthali and Kancha Kela were assayed against the enzymes α-amylase, α-glucosidase, acetylcholinesterase, β-glucuronidase and Angiotensin I Converting Enzyme, which are related to different diseased states like diabetes, Alzheimer's disease, hepatic disorder and cardiovascular diseases, respectively. The extracts inhibited all the enzymes except α-amylase by Musa X paradisiaca cv. Kanthali. Significantly high activities were observed in both the cultivated varieties for inhibiting the enzymes β-glucuronidase and Angiotensin I Converting Enzyme with respect to the known inhibitors of such enzymes silymarin and Lisinopril, respectively. The chemical constituents present in the methanol extracts were profiled following GC-MS based metabolomics approach. Eleven organic acids, seven sugars and sugar alcohols, six fatty acids, three phenols, two amino acids and a sterol could be identified.
Practical Applications
The male flowers of Musa X paradisiaca are cooked as vegetable in South-East Asia. The flowers are also useful in diabetes. Enzyme inhibitors have properties to prevent or control different noninfectious diseases. So, the flower extracts of two varieties of the plant were assayed for their activities against the glycosidases, acetylcholinesterase, β-glucuronidase and Angiotensin I Converting Enzyme. The activities of the flower extracts against the enzymes suggest that they may have beneficial effects in controlling diseases.read more
Citations
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Journal ArticleDOI
Angiotensin-I-Converting Enzyme (ACE)-Inhibitory Peptides from Plants.
Ceren Daskaya-Dikmen,Aysun Yücetepe,Funda Karbancioglu-Guler,Hayrettin Daşkaya,Beraat Özçelik +4 more
TL;DR: The current literature on plant-derived ACE-inhibitory peptides including their sources, production and structure, as well as their activity by in vitro and in vivo studies and their bioavailability are reviewed.
Journal ArticleDOI
An update on the health benefits promoted by edible flowers and involved mechanisms
Jingyun Zheng,Baiyi Lu,Baojun Xu +2 more
TL;DR: The aim of this review is to provide new findings on health effects of edible flowers since 2015, and some newly found phytochemicals such as polysaccharides were shown to be beneficial to human health.
Journal ArticleDOI
Essential oil of Piper betle L. leaves: Chemical composition, anti-acetylcholinesterase, anti-β-glucuronidase and cytotoxic properties
TL;DR: In this article, the essential oils were extracted from seven local varieties of P. betle L. leaves (Bangla, Bagerhati, Manikdanga, Meetha, Kalibangla, Chhaanchi and Ghanagete) with the aim to characterize the varieties on the basis of oil constituents and to study their enzyme inhibitory and cytotoxic properties.
Journal ArticleDOI
Antioxidant and anticancer potentials of edible flowers: where do we stand?
Sajad Fakhri,Merve Tomas,Esra Capanoglu,Yaseen Hussain,Fatemeh Abbaszadeh,Fatemeh Abbaszadeh,Baiyi Lu,Xiaolan Hu,Jian-Lin Wu,Liang Zou,Antonella Smeriglio,Jesus Simal-Gandara,Hui Cao,Jianbo Xiao,Jianbo Xiao,Haroon Khan +15 more
TL;DR: In this paper, the authors highlighted the phytochemical content and therapeutic applications of edible flowers, as well as their modulatory potential on the oxidative stress pathways and apoptotic/inflammatory mediators, resulting in anticancer effects.
References
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Journal ArticleDOI
A new and rapid colorimetric determination of acetylcholinesterase activity.
TL;DR: A photometric method for determining acetylcholinesterase activity of tissue extracts, homogenates, cell suspensions, etc., has been described and Kinetic constants determined by this system for erythrocyte eholinesterases are presented.
Journal ArticleDOI
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2·7 million participants
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Journal ArticleDOI
2013 Alzheimer's disease facts and figures
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TL;DR: This report provides information to increase understanding of the public health impact of Alzheimer's disease (AD), including incidence and prevalence, mortality rates, health expenditures and costs of care, and effect on caregivers and society in general.
Journal ArticleDOI
Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung
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TL;DR: A sensitive, fixed-time, spectrophotometric assay for angiotensin-converting enzyme measures the rate of production of hippuric acid from hippuryl-L -histidyl- L -leucine (HHL).
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