Journal ArticleDOI
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
Marc Decramer,Kenneth R. Chapman,Ronald Dahl,Peter Frith,Gilles Devouassoux,Carlos Cezar Fritscher,Ray Cameron,Muhammad Shoaib,David Lawrence,David Young,Danny McBryan +10 more
TLDR
Indacaterol and tiotropium provided clinically relevant improvements in lung function with comparable safety profiles and the present data offer evidence consistent with current guidelines.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2013-09-01. It has received 230 citations till now. The article focuses on the topics: Tiotropium bromide & Indacaterol.read more
Citations
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Journal ArticleDOI
The association of lung function and St. George's respiratory questionnaire with exacerbations in COPD: a systematic literature review and regression analysis.
Amber Martin,Jessica Marvel,Kyle Fahrbach,Sarah M. Cadarette,Teresa K. Wilcox,James F. Donohue +5 more
TL;DR: A significant association between improvements in FEV1 and SGRQ score and lower risk for COPD exacerbations is demonstrated, and will help inform clinical and formulary-making decisions while stimulating new research questions for future prospective studies.
Journal ArticleDOI
ALAT-2014 Chronic Obstructive Pulmonary Disease (COPD) Clinical Practice Guidelines: questions and answers.
Maria Montes de Oca,Maria Victorina Lopez Varela,Agustín Acuña,Eduardo Schiavi,María Alejandra Rey,José Roberto Jardim,Alejandro Casas,Antonio Tokumoto,Carlos A. Torres Duque,Alejandra Ramírez-Venegas,Gabriel García,Roberto Stirbulov,Aquiles Assunção Camelier,Miguel Bergna,Mark Cohen,Santiago Guzmán,Efraín Sánchez +16 more
TL;DR: Evidence reveals the existence of risk factors for COPD other than tobacco, as well as gender differences in disease presentation, and shows the benefit of screening in an at-risk population, and the predictive value use of multidimensional prognostic indexes.
Journal ArticleDOI
Dual Bronchodilation with Indacaterol Maleate/Glycopyrronium Bromide Compared with Umeclidinium Bromide/Vilanterol in Patients with Moderate-to-Severe COPD: Results from Two Randomized, Controlled, Cross-over Studies.
Edward Kerwin,Gary T. Ferguson,Shahin Sanjar,Thomas Goodin,Anthony Yadao,Robert Fogel,Samopriyo Maitra,Biswajit Sen,Tim Ayers,Donald Banerji +9 more
TL;DR: The data support the use of IND/GLY as an efficacious and well tolerated treatment option in patients with COPD, and the primary efficacy objective of non-inferiority of indacaterol/glycopyrrolate relative to UMEC/VI was not met.
Journal ArticleDOI
LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review
Paola Rogliani,Luigino Calzetta,Fulvio Braido,Mario Cazzola,Enrico Clini,Girolamo Pelaia,Andrea Rossi,Nicola Scichilone,Fabiano Di Marco +8 more
TL;DR: Evidence supporting the efficacy of LABA/LAMA FDCs for COPD is heterogeneous, particularly for TDI and SGRQ scores, exacerbation rates, ET, and IC.
Journal ArticleDOI
Revised (2018) COPD Clinical Practice Guideline of the Korean Academy of Tuberculosis and Respiratory Disease: A Summary.
Yong Bum Park,Chin Kook Rhee,Hyoung Kyu Yoon,Yeon-Mok Oh,Seong Yong Lim,Jin Hwa Lee,Kwang Ha Yoo,Joong Hyun Ahn +7 more
TL;DR: This guideline is expected to facilitate the treatment of patients with respiratory conditions by physicians as well other health care professionals and government personnel in South Korea.
References
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Journal ArticleDOI
Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
TL;DR: This research presents a novel and scalable approach called “Standardation of LUNG FUNCTION TESTing” that combines “situational awareness” and “machine learning” to solve the challenge of integrating nanofiltration into the energy system.
Journal ArticleDOI
A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.
TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
Journal ArticleDOI
The St George's Respiratory Questionnaire.
TL;DR: The St George's Respiratory Questionnaire is a standardized self-completed questionnaire for measuring impaired health and perceived well-being in airways disease and the background and rationale for its development are discussed together with an analysis of its performance.
Journal ArticleDOI
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
TL;DR: It is suggested that the frequency of exacerbations contributes to long term decline in lung function of patients with moderate to severe COPD.