Journal ArticleDOI
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
Marc Decramer,Kenneth R. Chapman,Ronald Dahl,Peter Frith,Gilles Devouassoux,Carlos Cezar Fritscher,Ray Cameron,Muhammad Shoaib,David Lawrence,David Young,Danny McBryan +10 more
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TLDR
Indacaterol and tiotropium provided clinically relevant improvements in lung function with comparable safety profiles and the present data offer evidence consistent with current guidelines.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2013-09-01. It has received 230 citations till now. The article focuses on the topics: Tiotropium bromide & Indacaterol.read more
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Chronic obstructive pulmonary disease - diagnosis and management of stable disease; a personalized approach to care, using the treatable traits concept based on clinical phenotypes. Position paper of the Czech Pneumological and Phthisiological Society
Jaromir Zatloukal,Kristián Brat,Katerina Neumannova,Eva Volakova,Karel Hejduk,Eva Kocova,Ondrej Kudela,Michal Kopecky,Marek Plutinsky,Vladimir Koblizek +9 more
TL;DR: This position paper has been drafted by experts from the Czech national board of diseases with bronchial obstruction and the Czech Pneumological and Phthisiological Society based on both the results of randomized controlled trials and data from cross-sectional and prospective real-life studies to ensure they are as close as possible to the context of daily clinical practice and the current health care system of the Czech Republic.
Journal ArticleDOI
COPD phenotypes and machine learning cluster analysis: A systematic review and future research agenda.
TL;DR: The last decade of research progress, which uses cluster analysis to identify COPD phenotypes, is systematically reviewed, providing a systematized account of the extant evidence, the strengths and weaknesses of the main methods used, identify gaps in the literature, and suggest recommendations for future research.
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The 2017 Global Initiative for Chronic Obstructive Lung Disease Report and Practice Implications for the Respiratory Therapist.
TL;DR: The 2017 GOLD report represents a major revision to GOLD strategy guidelines, the first such major revision in the last 5 years, and has significant implications for the diagnosis of COPD, the management of stable disease, and the treatment of exacerbations.
Journal ArticleDOI
Tiotropium/olodaterol versus tiotropium in Japanese patients with COPD: results from the DYNAGITO study.
Masakazu Ichinose,Masaharu Nishimura,Manabu Akimoto,Yasuhiro Kurotori,Yihua Zhao,Alberto de la Hoz,Michiaki Mishima +6 more
TL;DR: Combination therapy with TIO+OLO was more effective than TIO in reducing exacerbations and both treatments were well tolerated.
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Characteristics of COPD Patients Managed in Respiratory Medicine Departments in Spain, According to GOLD Groups and GesEPOC Clinical Phenotypes.
José Luis Izquierdo,Marc Miravitlles,Cristina Esquinas,Maite Pérez,Myriam Calle,José Luis López Campos,José Miguel Rodríguez González-Moro,Ciro Casanova,Cristóbal Esteban,Pilar de Lucas +9 more
TL;DR: En consultas de neumologia existe una elevada proporcion de pacientes EPOC con baja complejidad and un escaso uso of pruebas neumologicas.
References
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
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Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
TL;DR: This research presents a novel and scalable approach called “Standardation of LUNG FUNCTION TESTing” that combines “situational awareness” and “machine learning” to solve the challenge of integrating nanofiltration into the energy system.
Journal ArticleDOI
A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.
TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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The St George's Respiratory Questionnaire.
TL;DR: The St George's Respiratory Questionnaire is a standardized self-completed questionnaire for measuring impaired health and perceived well-being in airways disease and the background and rationale for its development are discussed together with an analysis of its performance.
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Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
TL;DR: It is suggested that the frequency of exacerbations contributes to long term decline in lung function of patients with moderate to severe COPD.