Journal ArticleDOI
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
Marc Decramer,Kenneth R. Chapman,Ronald Dahl,Peter Frith,Gilles Devouassoux,Carlos Cezar Fritscher,Ray Cameron,Muhammad Shoaib,David Lawrence,David Young,Danny McBryan +10 more
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TLDR
Indacaterol and tiotropium provided clinically relevant improvements in lung function with comparable safety profiles and the present data offer evidence consistent with current guidelines.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2013-09-01. It has received 230 citations till now. The article focuses on the topics: Tiotropium bromide & Indacaterol.read more
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Principaux messages de la première Biennale BPCO 2021 de la SPLF. Mieux comprendre pour innover
Julien Ancel,M. Gueçamburu,V. Marques da Silva,P. Schilfarth,Laura Boyer,Charles Pilette,Carl S. Martin,P. Devillier,Peter Glen Berger,Maeva Zysman,O. Le Rouzic,Jésus Gonzalez-Bermejo,Bruno Degano,Pierre-Régis Burgel,Ehsan Ahmed,N. Roche,Gaëtan Deslée +16 more
TL;DR: The first COPD biennial organized by the French Society of Respiratory Diseases (SPLF) took place on 17 December 2019 and discussed current knowledge regarding COPD pathophysiology, current treatments, research development, and future therapeutic approaches as mentioned in this paper .
Journal ArticleDOI
LABA/LAMA Fixed Dose Combination in Chronic Obstructive Pulmonary Disease: The Impact on Health-Related Quality of Life.
TL;DR: LABA/LAMA FDCs may be helpful in improving HRQoL, but because of the heterogeneity of performed trials, strong conclusions cannot be drawn.
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Revisión narrativa de la terapia inhalatoria en la EPOC
TL;DR: In this article , a comparison between the fixed combination LABA/LAMA versus LABA-CI in non-exacerbating patients, revealed a better control with LABA and LAMA.
Journal ArticleDOI
Возможности ингаляционной терапии по предупреждению обострений хронической обструктивной болезни легких. Заключение Совета экспертов Российского респираторного общества
С. Н. Авдеев,А. C. Белевский,З. Р. Айсанов,В. В. Архипов,И. В. Лещенко,С. И. Овчаренко,А. И. Синопальников,А. А. Визель,А. В. Емельянов,А. В. Жестков,К. А. Зыков,Н. А. Кузубова,Г. Г. Прозорова,Б. А. Черняк,Н. Л. Шапорова,Е. И. Шмелев +15 more
TL;DR: In this paper, the authors investigated the role of tiotropium/olodaterol combination over other inhaled therapies, such as inhaled corticosteroid/long-acting β2-agonist (ICS/LABA) combinations and long-acting muscarinic antagonist (LAMA)/LABA combinations, for risk reduction of moderate to severe exacerbations.
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Effects of indacaterol versus tiotropium on exercise tolerance in patients with moderate COPD: a pilot randomized crossover study.
Danilo C. Berton,Álvaro Huber dos Santos,Ivo Bohn,Rodrigo Quevedo de Lima,Vanderleia Breda,Paulo José Zimermann Teixeira,Paulo José Zimermann Teixeira +6 more
TL;DR: In patients with moderate COPD, tiotropium tends to improve Tlim in comparison with indacaterol, and future studies are required to confirm the findings and explore mechanistic explanations.
References
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Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Journal ArticleDOI
Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
TL;DR: This research presents a novel and scalable approach called “Standardation of LUNG FUNCTION TESTing” that combines “situational awareness” and “machine learning” to solve the challenge of integrating nanofiltration into the energy system.
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A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.
TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
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The St George's Respiratory Questionnaire.
TL;DR: The St George's Respiratory Questionnaire is a standardized self-completed questionnaire for measuring impaired health and perceived well-being in airways disease and the background and rationale for its development are discussed together with an analysis of its performance.
Journal ArticleDOI
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
TL;DR: It is suggested that the frequency of exacerbations contributes to long term decline in lung function of patients with moderate to severe COPD.