Journal ArticleDOI
Once-daily indacaterol versus tiotropium for patients with severe chronic obstructive pulmonary disease (INVIGORATE): a randomised, blinded, parallel-group study
Marc Decramer,Kenneth R. Chapman,Ronald Dahl,Peter Frith,Gilles Devouassoux,Carlos Cezar Fritscher,Ray Cameron,Muhammad Shoaib,David Lawrence,David Young,Danny McBryan +10 more
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TLDR
Indacaterol and tiotropium provided clinically relevant improvements in lung function with comparable safety profiles and the present data offer evidence consistent with current guidelines.About:
This article is published in The Lancet Respiratory Medicine.The article was published on 2013-09-01. It has received 230 citations till now. The article focuses on the topics: Tiotropium bromide & Indacaterol.read more
Citations
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Journal ArticleDOI
Acute bronchodilator responses to β2-agonist and anticholinergic agent in COPD: Their different associations with exacerbation.
Satoshi Konno,Hironi Makita,Masaru Suzuki,Kaoruko Shimizu,Hirokazu Kimura,Hiroki Kimura,Masaharu Nishimura +6 more
TL;DR: Increased cholinergic airway tone, which is reflected in the higher BDR only to anticholinergic agent, but not to β2-agonist, may be associated with exacerbation in COPD.
Journal ArticleDOI
Olodaterol for the treatment of chronic obstructive pulmonary disease: a narrative review.
TL;DR: Olodaterol improves lung function for 24 h and reduces rescue medication use and may also improve dyspnea, exercise tolerance, and health-related quality of life and is well tolerated with an acceptable cardiovascular and respiratory adverse event profile.
Journal ArticleDOI
Integrating Comorbidities and Phenotype-Based Medicine in Patient-Centered Medicine in COPD.
José Luis López-Campos,Borja Ruiz-Duque,Laura Carrasco-Hernandez,Laura Carrasco-Hernandez,Candelaria Caballero-Eraso,Candelaria Caballero-Eraso +5 more
TL;DR: Four major dilemmas in the search for a patient-centered approach to COPD management are addressed and how to combine them all in a single easy-to-use strategy is suggested.
Journal ArticleDOI
Glycopyrronium for chronic obstructive pulmonary disease: evidence and rationale for use from the GLOW trials
TL;DR: Glycopyrronium is a useful addition to the treatments for chronic obstructive pulmonary disease and had a similar effect on clinical outcomes with a faster onset of action than the long-acting muscarinic antagonist tiotropium.
Journal ArticleDOI
Evaluation of Malnutrition Risk in Lung Transplant Candidates Using the Nutritional Risk Index.
K. Chohan,Jeff Park,Sarah Dales,R.A. Varughese,Lisa Wickerson,Lianne G. Singer,Brooke Stewart,Dmitry Rozenberg +7 more
TL;DR: Malnutrition risk assessed with NRI was not prognostic of posttransplant outcomes in this retrospective cohort of lung transplant candidates, and LTx candidates with high malnutrition risk were able to maintain their weight pretransplant and demonstrated considerable weight gain in the first-year post Transplant.
References
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Journal ArticleDOI
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary.
Jørgen Vestbo,Suzanne S. Hurd,Alvar Agusti,Paul W. Jones,Claus Vogelmeier,Antonio Anzueto,Peter J. Barnes,Leonardo M. Fabbri,Fernando J. Martinez,Masaharu Nishimura,Robert A. Stockley,Don D. Sin,Roberto Rodriguez-Roisin +12 more
TL;DR: It is recommended that spirometry is required for the clinical diagnosis of COPD to avoid misdiagnosis and to ensure proper evaluation of severity of airflow limitation.
Journal ArticleDOI
Standardisation of spirometry
Martin R. Miller,John L. Hankinson,Vito Brusasco,Felip Burgos,Richard Casaburi,Allan L. Coates,Robert O. Crapo,Paul L. Enright,C.P.M. van der Grinten,P. Gustafsson,R. Jensen,D.C. Johnson,Neil R. MacIntyre,Roy T. McKay,Daniel Navajas,O. F. Pedersen,Riccardo Pellegrino,Giovanni Viegi,J. Wanger +18 more
TL;DR: This research presents a novel and scalable approach called “Standardation of LUNG FUNCTION TESTing” that combines “situational awareness” and “machine learning” to solve the challenge of integrating nanofiltration into the energy system.
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A self-complete measure of health status for chronic airflow limitation. The St. George's Respiratory Questionnaire.
TL;DR: The St. George's Respiratory Questionnaire is a valid measure of impaired health in diseases of chronic airflow limitation that is repeatable and sensitive andMultivariate analysis demonstrated that SGRQ scores summed a number of areas of disease activity.
Journal ArticleDOI
The St George's Respiratory Questionnaire.
TL;DR: The St George's Respiratory Questionnaire is a standardized self-completed questionnaire for measuring impaired health and perceived well-being in airways disease and the background and rationale for its development are discussed together with an analysis of its performance.
Journal ArticleDOI
Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
TL;DR: It is suggested that the frequency of exacerbations contributes to long term decline in lung function of patients with moderate to severe COPD.