One-pot synthesis of triazines as potential agents affecting cell differentiation
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A one-pot protocol was developed for swift functionalization of the 1,3,5-triazine core without the need of isolating intermediates, and tert-butyl, methyl, and ethyl ester derivatives of the target compounds were initially synthesized to facilitate purification.Abstract:
This paper outlines the synthesis of a number of structural analogs of 3-[(4,6-diphenoxy-1,3,5-triazin-2-yl)amino]benzoic acid which represent compounds with potential cardiogenetic activity. A one-pot protocol was developed for swift functionalization of the 1,3,5-triazine core without the need of isolating intermediates. The developed route starts from readily available 2,4,6-trichloro-1,3,5-triazine, displacing the chlorine atoms sequentially by aryloxy, arylamino, or arylthio moieties to enable access to molecules with three different substituents of this type in good yields. To facilitate purification, tert-butyl, methyl, and ethyl ester derivatives of the target compounds were initially synthesized. The tert-butyl esters could be readily hydrolyzed to the desired compounds, while reduction of the methyl and ethyl esters gave the corresponding benzylic alcohols in high yields, thereby expanding the substrate scope for future relevant cell assays.read more
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Cyanuric chloride as a potent catalyst for the reduction of curing temperature of benzoxazines
TL;DR: Cyanuric chloride (2,4,6-trichloro-1,3,5-triazine, TCT) was used as a catalyst to lower the ring opening polymerization (ROP) temperature of 1,3-benzoxazines as discussed by the authors.
Journal ArticleDOI
Synthesis, X-Ray Crystal Structures, and Preliminary Antiproliferative Activities of New s-Triazine-hydroxybenzylidene Hydrazone Derivatives
Assem Barakat,Assem Barakat,Fardous F. El-Senduny,Zainab M. Almarhoon,Hessa H. Al-Rasheed,Farid A. Badria,Abdullah Mohammed Al-Majid,Hazem A. Ghabbour,Ayman El-Faham,Ayman El-Faham +9 more
TL;DR: In this paper, a small library of Schiff-base compounds that encompasses s-triazine and (2 or 4)-hydroxylbenzylidene derivatives was reported.
Journal ArticleDOI
Synthesis, stability and printing properties of a novel 2‐sulphophenoxy‐4‐chloro‐s‐triazine reactive dye for ink‐jet printing of wool
TL;DR: In this article, the synthesis and characterisation of a new medium-reactivity reactive dye containing 2−sulphophenoxy−4−chloro−s−triazine, having enhanced the activity of the chlorine atom for further substitution by the functional groups carried by wool fiber, was reported.
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Triazine: An Important Building Block of Organic Materials for Solar Cell Application
TL;DR: In this paper , a review of the development of triazine-based organic materials for solar cell applications is presented, including organic solar cells, dye-sensitized solar cells and perovskite solar cells.
Journal ArticleDOI
Various Techniques for One-Pot Synthesis of 1,3,5-Triazine (s-Triazine) Derivatives: A Review
TL;DR: A review of one-pot synthesis of 1,3,5-triazine scaffolds can be found in this paper , where the authors highlight the various methodologies involved for 1-3-5 triazine synthesis.
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