Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
Reads0
Chats0
TLDR
In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.Abstract:
An adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations. The test statistic is a direct statistical analogue of the popular "funnel-graph." The number of component studies in the meta-analysis, the nature of the selection mechanism, the range of variances of the effect size estimates, and the true underlying effect size are all observed to be influential in determining the power of the test. The test is fairly powerful for large meta-analyses with 75 component studies, but has only moderate power for meta-analyses with 25 component studies. However, in many of the configurations in which there is low power, there is also relatively little bias in the summary effect size estimate. Nonetheless, the test must be interpreted with caution in small meta-analyses. In particular, bias cannot be ruled out if the test is not significant. The proposed technique has potential utility as an exploratory tool for meta-analysts, as a formal procedure to complement the funnel-graph.read more
Citations
More filters
Journal ArticleDOI
The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: A systematic review and meta-analysis.
Zobair M. Younossi,Zobair M. Younossi,Pegah Golabi,Leyla de Avila,James Paik,Manirath K. Srishord,Natsu Fukui,Ying Qiu,Leah Burns,Arian Afendy,Fatema Nader +10 more
TL;DR: Evidence is provided supporting high prevalence of NAFLD and NASH in patients with T2DM around the world and regional and global mean prevalence weighted by population size in each country were estimated and pooled using random-effects meta-analysis.
Journal ArticleDOI
Neoadjuvant Versus Adjuvant Systemic Treatment in Breast Cancer: A Meta-Analysis
TL;DR: Neoadjuvant therapy was apparently equivalent to adjuvant therapy in terms of survival and overall disease progression and was associated with a statistically significant increased risk of loco-regional recurrence when radiotherapy without surgery was adopted.
Journal ArticleDOI
Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies.
TL;DR: Overweight and obesity are associated with a dose-dependent increase in the odds of incident asthma in men and women, suggesting asthma incidence could be reduced by interventions targeting overweight and obesity.
Journal ArticleDOI
Prevalence, incidence and mortality from cardiovascular disease in patients with pooled and specific severe mental illness: a large-scale meta-analysis of 3,211,768 patients and 113,383,368 controls.
Christoph U. Correll,Marco Solmi,Nicola Veronese,Beatrice Bortolato,Stella Rosson,Paolo Santonastaso,Nita Thapa-Chhetri,Michele Fornaro,Davide Gallicchio,Enrico Collantoni,Giorgio Pigato,Angela Favaro,Francesco Monaco,Cristiano A. Köhler,Davy Vancampfort,Philip B. Ward,Fiona Gaughran,André F. Carvalho,Brendon Stubbs +18 more
TL;DR: This large‐scale meta‐analysis confirms that SMI patients have significantly increased risk of CVD and CVD‐related mortality, and that elevated body mass index, antipsychotic use, andCVD screening and management require urgent clinical attention.
References
More filters
Journal ArticleDOI
Publication bias in clinical research
TL;DR: The presence of publication bias in a cohort of clinical research studies is confirmed and it is suggested that conclusions based only on a review of published data should be interpreted cautiously, especially for observational studies.
Book
Summing Up: The Science of Reviewing Research
TL;DR: A Checklist for Evaluating Reviews Reference Index as discussed by the authors is a checklist for evaluating reviews that is based on a reviewing strategy and a review review strategy that is organized by the division of labor.
Journal ArticleDOI
Summing Up: The Science of Reviewing Research.
TL;DR: In this article, the authors summarize the science of reviewing research, including the review process, the review review process itself, and the reviewer's role in reviewing research articles, as well as the process of reviewing the review articles.
Journal ArticleDOI
Factors Influencing Publication of Research Results: Follow-up of Applications Submitted to Two Institutional Review Boards
TL;DR: There was evidence of publication bias in that for both institutional review boards there was an association between results reported to be significant and publication and contrary to popular opinion, publication bias originates primarily with investigators, not journal editors.
Journal ArticleDOI
Publication bias : a problem in interpreting medical data
Colin B. Begg,Jesse A. Berlin +1 more
TL;DR: In this paper, the authors review the available research, discuss alternative suggestions for conducting unbiased meta-analysis and suggest some scientific policy measures which could improve the quality of published data in the long term.