Journal ArticleDOI
Optimised parameters for A-DNA and B-DNA
TLDR
The molecular structures presented have the most probable values of bond-lengths, bond-angles and furanose ring conformations as defined by accurate X-ray crystallographic analyses of relevant monomers.About:
This article is published in Biochemical and Biophysical Research Communications.The article was published on 1972-06-28. It has received 895 citations till now. The article focuses on the topics: Furanose & A-DNA.read more
Citations
More filters
Journal ArticleDOI
Scissors-grip model for DNA recognition by a family of leucine zipper proteins
TL;DR: An evaluation of the properties of conserved amino acids within the basic region of 11 deduced protein sequences, coupled with the observation that they are located at an invariant distance from the leucine zipper, has led to the formulation of a "scissors-grip" model for DNA binding.
Journal ArticleDOI
The Definition of Generalized Helicoidal Parameters and of Axis Curvature for Irregular Nucleic Acids
Richard Lavery,Heinz Sklenar +1 more
TL;DR: An algorithm is presented which solves the problem of obtaining a rigorous helicoidal description of an irregular nucleic acid segment by definition of a function describing simultaneously the curvature of the nucleic acids segment and the corresponding stepwise variation of helicoidal parameters along the segment.
Journal ArticleDOI
Structure of a B-DNA dodecamer: III. Geometry of hydration
TL;DR: The dodecamer d(cpGpCpGPGpApApApTpTpPTpC pGpG pCpCPG pG pApAp ApApT pTp TpG PGp CpG-C-G-A A-A-T-T T-T, C-Gg-Cc-Cg-Gp Gp CcG-G, GpGgp CgGpP GpCcG p Cgp G
Journal ArticleDOI
Structure of a B-DNA dodecamer: II. Influence of base sequence on helix structure☆
TL;DR: The correlation of the digestion patterns in solution and helical twist in the crystal argues for the essential identity of the helix structure in the two environments.
Journal ArticleDOI
The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements
TL;DR: The crystal structure of the fully specific complex between the DNA-binding domain from the estrogen receptor and DNA reveals how the protein recognizes its own half site sequence rather than that of the related glucocorticoid receptor, which differs by only two base pairs.
References
More filters
Journal ArticleDOI
Stereochemistry of nucleic acids and their constituents.† IV. Allowed and preferred conformations of nucleosides, nucleoside mono-, di-, tri-, tetraphosphates, nucleic acids and polynucleotides‡
TL;DR: In this article, a uniform notation and convention is suggested to describe the torsional angles in nucleic acids and their derivatives, and a plausible structure and conformation for the ATPM2− backbound complex is presented.
Journal ArticleDOI
The molecular configuration of deoxyribonucleic acid: II. Molecular models and their fourier transforms
Robert Langridge,D.A. Marvin,W. E. Seeds,H. R. Wilson,C. W. Hooper,M. H. F. Wilkins,L. D. Hamilton +6 more
TL;DR: In this article, the Fourier transform of the structure has been calculated, and comparison with the X-ray data described in Part I shows that the model needs modifying, and various models were built and adjusted until reasonable agreement was obtained between the Fouriers transform, averaged by rotation about the helix axis, and the observed 2D intensity data.
Journal ArticleDOI
The molecular configuration of deoxyribonucleic acid: IV. X-ray diffraction study of the A form
TL;DR: Detailed three-dimensional X-ray diffraction data from microcrystalline fibres of the sodium salt of DNA are described, confirming the correctness of the Watson-Crick scheme for base-pairing and eliminating the possibility that DNA molecules might have a left-handed configuration.
Book ChapterDOI
The crystal structures of purines, pyrimidines and their intermolecular complexes.
Donald Voet,Alexander Rich +1 more
TL;DR: The chapter reviews the structure arid conformation of the sugar and the phosphate components of nucleosides, nucleotides, and nucleic acids, and their steric relationship to the purines and pyrimidines, and reviews the diversity of the H-bonding potentiality of the nucleic acid bases.
Journal ArticleDOI
Least‐squares refinement of the crystal and molecular structures of DNA and RNA from X‐ray data and standard bond lengths and angles
TL;DR: In this paper, the arrangement of the carbonyl oxygen [O(1\")] around the N H + group in valine hydrochloride or in 7-glycine was described.
Related Papers (5)
The Definition of Generalized Helicoidal Parameters and of Axis Curvature for Irregular Nucleic Acids
Richard Lavery,Heinz Sklenar +1 more