Journal ArticleDOI
Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research
TLDR
In this article, a percutaneous needle biopsy of skeletal muscle in Physiological and Clinical Research is described, and the authors present a detailed discussion of the procedure and the results.Abstract:
(1975). Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 35, No. 7, pp. 609-616.read more
Citations
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Conjugated Linoleic Acid Suppresses Myogenic Gene Expression in a Model of Human Muscle Cell Inflammation
TL;DR: It is demonstrated that TNFalpha can have specific regulatory effects on myogenic genes in primary human muscle cells and a postulated antiinflammatory role of CLA in myogenesis appears more complex, with an indication that CLA may have a negative effect on this process.
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A "human knockout" model to investigate the influence of the α-actinin-3 protein on exercise-induced mitochondrial adaptations.
Ioannis D Papadimitriou,Ioannis D Papadimitriou,Nir Eynon,Xu Yan,Fiona Munson,Macsue Jacques,Jujiao Kuang,Sarah Voisin,Kathryn N. North,David Bishop,David Bishop +10 more
TL;DR: Loss of α-actinin-3 is not associated with higher baseline endurance-related phenotypes, or greater adaptations to endurance exercise training in humans, in contrast to results in mice.
Journal ArticleDOI
Methodological approaches to the study of metabolism across individual tissues in man.
Faidon Magkos,Labros S. Sidossis +1 more
TL;DR: Clearly, advances in the use, performance, and applications of available methods are expected to provide improved and more powerful tools for the metabolic investigation of organs and tissues in humans in vivo.
Journal ArticleDOI
Microvascular Function Is Impaired after Short-Term Immobilization in Healthy Men.
TL;DR: The study shows that 2 wk of immobilization impairs leg microvascular endothelial function and prostacyclin formation but that 4 wK of intense aerobic exercise training restores the function.
Journal ArticleDOI
Nutrient ingestion increased mTOR signaling, but not hVps34 activity in human skeletal muscle after sprint exercise.
Håkan Rundqvist,Håkan Rundqvist,Mats Lilja,Mats Lilja,Olav Rooyackers,Krzysztofa Odrzywol,James Murray,Mona Esbjörnsson,Mona Esbjörnsson,Eva Jansson,Eva Jansson +10 more
TL;DR: On the contrary to the hypothesis, no increase in activation of hVps34 was found following sprint exercise in EAA + Carb condition, however, the results support an activation of mTOR during this condition and does not exclude the permissive role of h Vps34 in mediating the amino acid‐induced activation ofmTOR and muscle protein synthesis.
References
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Journal ArticleDOI
Diet, Muscle Glycogen and Physical Performance
TL;DR: It has been shown that the glycogen content and, consequently, the long-term work capacity can be appreciably varied by instituting different diets after glycogen depletion.
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Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values.
TL;DR: Variation in muscle content of ATP, ATP + ADP + AMP, phosphorylcreatine (PC), creatine (Cr), PC + Cr, and glycogen, between legs, between sites on the same muscle, or as a result of error introduced during analysis, was small compared with the between-individuals variance.
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Intracellular free amino acid concentration in human muscle tissue.
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Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling rates
TL;DR: Glycogen depletion pattern in human skeletal muscle fibres was studied after bicycle exercise of varying intensity performed at different pedalling rates.
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Muscle Glycogen Synthesis after Exercise : an Enhancing Factor localized to the Muscle Cells in Man
Jonas Bergström,Eric Hultman +1 more
TL;DR: Goldstein1 has shown that a humoral factor, which decreases the blood glucose concentration, is released during exercise and it is known that the insulin requirement decreases in diabetic subjects during exercise.