Journal ArticleDOI
Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research
TLDR
In this article, a percutaneous needle biopsy of skeletal muscle in Physiological and Clinical Research is described, and the authors present a detailed discussion of the procedure and the results.Abstract:
(1975). Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 35, No. 7, pp. 609-616.read more
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Iconographies supplémentaires de l'article : Explorations de la fonction musculaire par spectrométrie et imagerie de résonance magnétique
TL;DR: P MRS has proved particularly useful in the therapeutic follow-up of palliative therapies (coenzyme Q treatment of mitochondriopathies) and in family investigations and is now an accepted diagnostic tool in the array of tests which are used to characterize muscle disorders in clinical routine.
Journal ArticleDOI
No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults.
Roland W. J. Hangelbroek,Anouk M.M. Vaes,Mark V. Boekschoten,Lex B. Verdijk,Guido J. E. J. Hooiveld,Luc J. C. van Loon,Lisette C. P. G. M. de Groot,Sander Kersten +7 more
TL;DR: Findings indicate that vitamin D supplementation has no effects on skeletal muscle gene expression, suggesting that skeletal muscle may not be a direct target of vitamin D in older adults.
Journal ArticleDOI
Regeneration of Mitochondrial Function in Gastrocnemius Muscle in Peripheral Arterial Disease After Successful Revascularisation.
Alexandra Gratl,Alexandra Gratl,Jan Paul Frese,Fiona Speichinger,Dominik Pesta,Andreas Frech,Safwan Omran,Andreas Greiner +7 more
TL;DR: It has been shown that the initially impaired mitochondrial function and content can normalise after revascularisation, and mitochondrial respiration normalised to CSA in oxidative phosphorylation and electron transfer capacity was significantly reduced post-operatively.
Journal ArticleDOI
Lipid droplet dynamics and insulin sensitivity upon a 5-day high-fat diet in Caucasians and South Asians.
Anne Gemmink,Leontine E. H. Bakker,Bruno Guigas,Esther Kornips,Gert Schaart,A. Edo Meinders,Ingrid M. Jazet,Matthijs K. C. Hesselink +7 more
TL;DR: Data indicate that in Caucasians, PLIN5 may be protective against HFHC-diet induced insulin resistance, which for reasons not yet understood is not observed in South Asians, who possess increased lipid peroxidation levels.
Journal ArticleDOI
Effect of Aerobic Exercise Training and Deconditioning on Oxidative Capacity and Muscle Mitochondrial Enzyme Machinery in Young and Elderly Individuals.
Andreas M. Fritzen,Søren Peter Andersen,Khaled Abdul Nasser Qadri,Frank D. Thøgersen,Thomas Krag,Mette Cathrine Ørngreen,John Vissing,Tina D. Jeppesen +7 more
TL;DR: It is found that elderly have a physiological normal ability to improve aerobic capacity and mitochondrial function with aerobic training compared to young individuals, but had a faster decline in endurance performance and muscle mitochondrial enzyme activity after deconditioning, suggesting an age-related issue in maintaining oxidative metabolism.
References
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Diet, Muscle Glycogen and Physical Performance
TL;DR: It has been shown that the glycogen content and, consequently, the long-term work capacity can be appreciably varied by instituting different diets after glycogen depletion.
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Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values.
TL;DR: Variation in muscle content of ATP, ATP + ADP + AMP, phosphorylcreatine (PC), creatine (Cr), PC + Cr, and glycogen, between legs, between sites on the same muscle, or as a result of error introduced during analysis, was small compared with the between-individuals variance.
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Intracellular free amino acid concentration in human muscle tissue.
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Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling rates
TL;DR: Glycogen depletion pattern in human skeletal muscle fibres was studied after bicycle exercise of varying intensity performed at different pedalling rates.
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Muscle Glycogen Synthesis after Exercise : an Enhancing Factor localized to the Muscle Cells in Man
Jonas Bergström,Eric Hultman +1 more
TL;DR: Goldstein1 has shown that a humoral factor, which decreases the blood glucose concentration, is released during exercise and it is known that the insulin requirement decreases in diabetic subjects during exercise.