Journal ArticleDOI
Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research
TLDR
In this article, a percutaneous needle biopsy of skeletal muscle in Physiological and Clinical Research is described, and the authors present a detailed discussion of the procedure and the results.Abstract:
(1975). Percutaneous Needle Biopsy of Skeletal Muscle in Physiological and Clinical Research. Scandinavian Journal of Clinical and Laboratory Investigation: Vol. 35, No. 7, pp. 609-616.read more
Citations
More filters
Journal ArticleDOI
Augmenting muscle diacylglycerol and triacylglycerol content by blocking fatty acid oxidation does not impede insulin sensitivity
Silvie Timmers,Miranda Nabben,Madeleen Bosma,Bianca W. J. van Bree,Ellen Lenaers,Denis van Beurden,Gert Schaart,Margriet S. Westerterp-Plantenga,Wolfgang Langhans,Matthijs K. C. Hesselink,Vera B. Schrauwen-Hinderling,Patrick Schrauwen +11 more
TL;DR: Results show that a reduction in fat oxidation leading to accumulation of muscle DAG does not necessarily lead to insulin resistance, as the reduction inFat oxidation may activate AMPK, and this effect was accompanied by increased phosphorylation of AMP-activated protein kinase (AMPK).
Journal ArticleDOI
Blood ammonia and lactate as markers of muscle metabolites during leg press exercise.
Esteban M. Gorostiaga,Ion Navarro-Amézqueta,Jose A. L. Calbet,Luis Sánchez-Medina,Roser Cussó,Mario Guerrero,Cristina Granados,Miriam González-Izal,Javier Ibáñez,Mikel Izquierdo +9 more
TL;DR: The decline in mechanical power output can be used to indirectly estimate blood ammonia and lactate during leg press exercise to estimate the functional state of the muscle contractile machinery with regard to muscle lactate and adenosine triphosphate (ATP) levels.
Journal ArticleDOI
Primary human muscle precursor cells obtained from young and old donors produce similar proliferative, differentiation and senescent profiles in culture
Mansour Alsharidah,Norman R. Lazarus,Tomasz E George,Chibeza C. Agley,Cristiana P. Velloso,Stephen D. R. Harridge +5 more
TL;DR: The data strongly suggest that MPCs from young and elderly people have similar myogenic behaviour, compared with cells from the same individuals in the non‐senescent state.
Journal ArticleDOI
Resistance exercise increases NF-κB activity in human skeletal muscle.
Luke Vella,Marissa K. Caldow,Amy E. Larsen,Daniella Tassoni,Paul A. Della Gatta,Petra Gran,Aaron P. Russell,David Cameron-Smith +7 more
TL;DR: In this paper, the effects of a single bout of intense resistance exercise on NF-κB signaling in human skeletal muscle were investigated, showing an increase in protein levels and nuclear localization at 2 and 4 hours post-exercise.
Journal ArticleDOI
Oral glucose ingestion attenuates exercise-induced activation of 5'-AMP-activated protein kinase in human skeletal muscle.
Thorbjorn Akerstrom,Jesper B. Birk,Ditte Kjærsgaard Klein,Christian Erikstrup,Peter Plomgaard,Bente Klarlund Pedersen,Jørgen F. P. Wojtaszewski +6 more
TL;DR: It is concluded that oral glucose ingestion attenuates the exercise-induced activation of alpha2-AMPK, bringing further support for a fuel-sensing role of AMPK in skeletal muscle.
References
More filters
Journal ArticleDOI
Diet, Muscle Glycogen and Physical Performance
TL;DR: It has been shown that the glycogen content and, consequently, the long-term work capacity can be appreciably varied by instituting different diets after glycogen depletion.
Journal ArticleDOI
Glycogen, glycolytic intermediates and high-energy phosphates determined in biopsy samples of musculus quadriceps femoris of man at rest. Methods and variance of values.
TL;DR: Variation in muscle content of ATP, ATP + ADP + AMP, phosphorylcreatine (PC), creatine (Cr), PC + Cr, and glycogen, between legs, between sites on the same muscle, or as a result of error introduced during analysis, was small compared with the between-individuals variance.
Journal ArticleDOI
Intracellular free amino acid concentration in human muscle tissue.
Journal ArticleDOI
Selective glycogen depletion pattern in human muscle fibres after exercise of varying intensity and at varying pedalling rates
TL;DR: Glycogen depletion pattern in human skeletal muscle fibres was studied after bicycle exercise of varying intensity performed at different pedalling rates.
Journal ArticleDOI
Muscle Glycogen Synthesis after Exercise : an Enhancing Factor localized to the Muscle Cells in Man
Jonas Bergström,Eric Hultman +1 more
TL;DR: Goldstein1 has shown that a humoral factor, which decreases the blood glucose concentration, is released during exercise and it is known that the insulin requirement decreases in diabetic subjects during exercise.