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Journal ArticleDOI

Pharmacological interventions for daytime sleepiness and sleep disorders in Parkinson's disease: Systematic review and meta-analysis.

TLDR
Single study results suggest that doxepin and YXQN granules might be efficacious, while pergolide may be deleterious for insomnia and that rivastigmine may be used to treat RBD in PD patients, but there is insufficient evidence to support or refute the efficacy of any of these interventions.
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This article is published in Parkinsonism & Related Disorders.The article was published on 2016-06-01. It has received 79 citations till now. The article focuses on the topics: Excessive daytime sleepiness & Epworth Sleepiness Scale.

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Consort

王林, +1 more
TL;DR: In this paper, the authors present the consolidated standards of reporting trials (CSTT) for the first time, and propose a set of guidelines for reporting trials, including the following:
Journal ArticleDOI

Sleep Disturbance, Cognitive Decline, and Dementia: A Review.

TL;DR: Evidence linking sleep disturbance and dementia is summarized, which highlights the potential importance of identifying and treating sleep problems and disorders in middle‐aged and older adults as a strategy to prevent cognitive decline and dementia.
Journal ArticleDOI

The Treatment of Sleep Disorders in Parkinson’s Disease: From Research to Clinical Practice

TL;DR: The appropriate diagnosis and treatment of SDs in PD can lead to the consolidation of nocturnal sleep, the enhancement of daytime alertness, and the amelioration of the quality of life of the patients.
Journal ArticleDOI

Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus.

TL;DR: It is shown that chemogenetic activation of A2AR neurons in specific subregions of the striatum induced a remarkable increase in non-rapid eye movement (NREM) sleep and led to a significant decrease of NREM sleep at active period, but not inactive period of mice.
References
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Journal ArticleDOI

CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials

TL;DR: The Consort 2010 Statement as discussed by the authors has been used worldwide to improve the reporting of randomised controlled trials and has been updated by Schulz et al. in 2010, based on new methodological evidence and accumulating experience.
Journal ArticleDOI

Non-motor symptoms of Parkinson's disease: diagnosis and management

TL;DR: Some non-motor symptoms of Parkinson's disease, including depression, constipation, pain, genitourinary problems, and sleep disorders, can be improved with available treatments and need the introduction of novel non-dopaminergic drugs.
Journal ArticleDOI

Incidence of Parkinson’s Disease: Variation by Age, Gender, and Race/Ethnicity

TL;DR: The data suggest that the incidence of Parkinson's disease varies by race/ethnicity, and the age- and gender-adjusted rate per 100,000 was highest among Hispanics.
Journal ArticleDOI

Non-motor symptoms of Parkinson's disease: dopaminergic pathophysiology and treatment

TL;DR: The dopaminergic basis of the range of non-motor symptoms that occur in PD such as depression, apathy, sleep disorders (including rapid-eye movement sleep behaviour disorder), and erectile dysfunction are investigated.
Journal ArticleDOI

Clinical Guideline for the Evaluation and Management of Chronic Insomnia in Adults

TL;DR: This clinical guideline is to provide clinicians with a practical framework for the assessment and disease management of chronic adult insomnia, using existing evidence-based insomnia practice parameters where available, and consensus-based recommendations to bridge areas where such parameters do not exist.
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