Plasma-activated water: An alternative disinfectant for S protein inactivation to prevent SARS-CoV-2 infection.
Li Guo,Zhiqian Yao,Lu Yang,Hao Zhang,Yu Qi,Lu Gou,Wang Xi,Dingxin Liu,Lei Zhang,Yilong Cheng,Xiaohua Wang,Mingzhe Rong,Hailan Chen,Michael G. Kong +13 more
TLDR
In this article, the authors used the RBD of the spike protein of SARS-CoV-2 S protein to study the molecular details and showed that the binding activity was inactivated by plasma-activated water through RBD modification.About:
This article is published in Chemical Engineering Journal.The article was published on 2021-10-01 and is currently open access. It has received 95 citations till now.read more
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The role of disinfectants and sanitizers during COVID-19 pandemic: advantages and deleterious effects on humans and the environment.
Kuldeep Dhama,Shailesh Kumar Patel,Rakesh Kumar,Rupali Masand,Jigyasa Rana,Mohd Iqbal Yatoo,Ruchi Tiwari,Khan Sharun,Ranjan K. Mohapatra,Senthilkumar Natesan,Manish Dhawan,Tauseef Ahmad,Talha Bin Emran,Yashpal Singh Malik,Harapan Harapan +14 more
TL;DR: In this paper, the role of disinfectants and sanitizers in the control and prevention of the current pandemic and highlights updated disinfection techniques against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
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Applications of Cold Atmospheric Pressure Plasma Technology in Medicine, Agriculture and Food Industry
TL;DR: In this paper, cold atmospheric pressure plasma (CAPP) technology has received substantial attention due to its valuable properties including operational simplicity, low running cost, and environmental friendliness, which can be used to generate plasma at atmospheric pressure and low temperature.
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Construction and applications of SARS-CoV-2 pseudoviruses: a mini review.
Minghai Chen,Xian-En Zhang +1 more
TL;DR: In this paper, the authors discuss the construction of SARS-CoV-2 pseudoviruses based on different packaging systems, current applications, limitations, and further explorations.
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Low-Temperature Plasma for Biology, Hygiene, and Medicine: Perspective and Roadmap
TL;DR: An overview of where plasma research is at today and innovative concepts and approaches to overcome present challenges and take the field to the next level can be found in this article , where a team of experts took an in-depth look at the various applications of plasma in hygiene, decontamination, and medicine, made critical analysis, and proposed ideas and concepts that should help the research community focus their efforts on clear and practical steps necessary to keep the field advancing for decades to come.
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Degradation of contaminants in plasma technology: An overview
TL;DR: The information of plasma technologies applications for environmental clean-up on treating and degrading metals, metalloids, dyes, biomass, antibiotics, pesticides, volatile organic compounds (VOCs), bacteria, virus and fungi is compiled and organized in the review article as mentioned in this paper .
References
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SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann,Hannah Kleine-Weber,Simon Schroeder,Nadine Krüger,Tanja Herrler,Sandra Erichsen,Tobias S. Schiergens,Georg Herrler,Nai Huei Wu,Andreas Nitsche,Marcel A. Müller,Christian Drosten,Christian Drosten,Stefan Pöhlmann +13 more
TL;DR: It is demonstrated that SARS-CoV-2 uses the SARS -CoV receptor ACE2 for entry and the serine protease TMPRSS2 for S protein priming, and it is shown that the sera from convalescent SARS patients cross-neutralized Sars-2-S-driven entry.
Journal ArticleDOI
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.
Daniel Wrapp,Nianshuang Wang,Kizzmekia S. Corbett,Jory A. Goldsmith,Ching-Lin Hsieh,Olubukola M. Abiona,Barney S. Graham,Jason S. McLellan +7 more
TL;DR: The authors show that this protein binds at least 10 times more tightly than the corresponding spike protein of severe acute respiratory syndrome (SARS)–CoV to their common host cell receptor, and test several published SARS-CoV RBD-specific monoclonal antibodies found that they do not have appreciable binding to 2019-nCoV S, suggesting that antibody cross-reactivity may be limited between the two RBDs.
Journal ArticleDOI
First Case of 2019 Novel Coronavirus in the United States.
Michelle Holshue,Chas DeBolt,Scott Lindquist,Kathy H Lofy,John Wiesman,Hollianne Bruce,Christopher Spitters,Keith M. Marzilli Ericson,Sara Wilkerson,Ahmet Tural,George Diaz,Amanda C. Cohn,LeAnne Fox,Anita Patel,Susan I. Gerber,Lindsay Kim,Suxiang Tong,Xiaoyan Lu,Steve Lindstrom,Mark A. Pallansch,William C. Weldon,Holly M. Biggs,Timothy M. Uyeki,Satish K. Pillai +23 more
TL;DR: This case highlights the importance of close coordination between clinicians and public health authorities at the local, state, and federal levels, as well as the need for rapid dissemination of clinical information related to the care of patients with this emerging infection.
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Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor.
Jun Lan,Jiwan Ge,Jinfang Yu,Sisi Shan,Huan Zhou,Shilong Fan,Qi Zhang,Xuanling Shi,Qisheng Wang,Linqi Zhang,Xinquan Wang +10 more
TL;DR: High-resolution crystal structures of the receptor-binding domain of the spike protein of SARS-CoV-2 and SARS -CoV in complex with ACE2 provide insights into the binding mode of these coronaviruses and highlight essential ACE2-interacting residues.
Journal ArticleDOI
Structural basis of receptor recognition by SARS-CoV-2.
Jian Shang,Gang Ye,Ke Shi,Yushun Wan,Chuming Luo,Hideki Aihara,Qibin Geng,Ashley Auerbach,Fang Li +8 more
TL;DR: This study determines the crystal structure of the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 (engineered to facilitate crystallization) in complex with ACE2 and sheds light on the structural features that increase its binding affinity to ACE2.