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Plasmodium: The fine structure of malarial parasites

Masamichi Aikawa
- 01 Oct 1971 - 
- Vol. 30, Iss: 2, pp 284-320
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This article is published in Experimental Parasitology.The article was published on 1971-10-01. It has received 204 citations till now.

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Citations
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Erythrocyte entry by malarial parasites. A moving junction between erythrocyte and parasite

TL;DR: Invasion of erythrocytes by merozoites of the monkey malaria, Plasmodium knowlesi, was investigated by electron microscopy and the movement of the junction during invasion is an important component of the mechanism by which themerozoite enters the ery Throcyte.
Journal ArticleDOI

Cytoskeleton of Apicomplexan Parasites

TL;DR: The unusual properties of actin and myosin in the Apicomplexa, the highly stereotyped microtubule populations in apicOMplexans, and a network of recently discovered novel intermediate filament-like elements in these parasites are discussed.
Journal ArticleDOI

A malarial cysteine proteinase is necessary for hemoglobin degradation by Plasmodium falciparum.

TL;DR: The Mr 28,000 cysteine proteinase has a critical, perhaps rate-limiting, role in hemoglobin degradation within the food vacuole of Plasmodium falciparum and specific inhibitors of this enzyme might provide new means of antimalarial chemotherapy.
Journal ArticleDOI

Fine structure of human malaria in vitro.

TL;DR: The erythrocytic cycle of the human malaria parasite, Plasmodium, falciparum, was examined by electron microscopy and the time of appearance of knobs on cells in vitro correlates with the life cycle stage of parasites which are sequestered from the peripheral circulation in vivo.
References
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THE USE OF LEAD CITRATE AT HIGH pH AS AN ELECTRON-OPAQUE STAIN IN ELECTRON MICROSCOPY

TL;DR: The stain reported here differs from previous alkaline lead stains in that the chelating agent, citrate, is in sufficient excess to sequester all lead present, and is less likely to contaminate sections.
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Improvements in epoxy resin embedding methods.

TL;DR: Epoxy embedding methods of Glauert and Kushida have been modified so as to yield rapid, reproducible, and convenientembedding methods for electron microscopy.
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Cytochemistry and electron microscopy. The preservation of cellular ultrastructure and enzymatic activity by aldehyde fixation.

TL;DR: A postfixation in osmium tetroxide, even after long periods of storage, developed an image that—notable in the case of glutaraldehyde—was largely indistinguishable from that of tissues fixed under optimal conditions with osmia tetroxides alone.
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