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Journal ArticleDOI

Population biology of infectious diseases: Part II

Robert M. May, +1 more
- 02 Aug 1979 - 
- Vol. 280, Iss: 5722, pp 455-461
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TLDR
Consideration is given to the relation between the ecology and evolution of the transmission processes and the overall dynamics, and to the mechanisms that can produce cyclic patterns, or multiple stable states, in the levels of infection in the host population.
Abstract
If the host population is taken to be a dynamic variable (rather than constant, as conventionally assumed), a wider understanding of the population biology of infectious diseases emerges. In this first part of a two-part article, mathematical models are developed, shown to fit data from laboratory experiments, and used to explore the evolutionary relations among transmission parameters. In the second part of the article, to be published in next week's issue, the models are extended to include indirectly transmitted infections, and the general implications for infectious diseases are considered.

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Citations
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Behaviour of Australian rainforest stream frogs may affect the transmission of chytridiomycosis.

TL;DR: Interspecific variation in transmission probability may, therefore, play a large role in determining why chytridiomycosis drives some populations to extinction and not others.
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Do Threatened Hosts Have Fewer Parasites? A Comparative Study in Primates

TL;DR: Differences in parasite richness relative to host threat status are demonstrated, indicating that human activities and host characteristics that increase the extinction risk of wild animal species may lead simultaneously to the loss of parasites.
Journal ArticleDOI

Disease and the dynamics of extinction

TL;DR: Two very different infectious diseases that are currently threatening to cause extinctions in Australia, Amphibian chytridiomycosis and Tasmanian devil facial tumour disease, provide an unusual opportunity to investigate the processes of disease-induced extinction and possible management strategies.
Journal ArticleDOI

The use of mathematical models in the epidemiological study of infectious diseases and in the design of mass immunization programmes.

TL;DR: Community-based immunization is the primary method available today by which to reduce the scale of morbidity, and, in certain countries, mortality, associated with the most common childhood viral and bacterial infections.
Journal ArticleDOI

An epidemic model of a vector-borne disease with direct transmission and time delay

TL;DR: In this article, the authors considered an epidemic model of a vector-borne disease which has direct mode of transmission in addition to the vector-mediated transmission, and they considered both a baseline ODE version of the model, and, a differential-delay model with a discrete time delay.
References
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Journal ArticleDOI

A contribution to the mathematical theory of epidemics

TL;DR: In this article, the authors considered the problem of finding a causal factor which appears to be adequate to account for the magnitude of the frequent epidemics of disease which visit almost every population.

A Contribution to the Mathematical Theory of Epidemics.

TL;DR: The present communication discussion will be limited to the case in which all members of the community are initially equally susceptible to the disease, and it will be further assumed that complete immunity is conferred by a single infection.
Journal ArticleDOI

The Natural Regulation of Animal Numbers

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