Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study.
Rong Hui Du,Li Rong Liang,Cheng Qing Yang,Wen Wang,Tan Ze Cao,Ming Li,Guang Yun Guo,Juan Du,Chun Lan Zheng,Qi Zhu,Ming Hu,Xu Yan Li,Peng Peng,Huan-Zhong Shi +13 more
TLDR
Age ≥65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3+CD8+ T-cells ≤75 cells·μL−1 and cardiac troponin I ≥0.05 ng·mL−1 were four risk factors predicting high mortality of COVID-19 pneumonia patients.Abstract:
The aim of this study was to identify factors associated with the death of patients with COVID-19 pneumonia caused by the novel coronavirus SARS-CoV-2. All clinical and laboratory parameters were collected prospectively from a cohort of patients with COVID-19 pneumonia who were hospitalised to Wuhan Pulmonary Hospital (Wuhan City, Hubei Province, China) between 25 December 2019 and 7 February 2020. Univariate and multivariate logistic regression was performed to investigate the relationship between each variable and the risk of death of COVID-19 pneumonia patients. In total, 179 patients with COVID-19 pneumonia (97 male and 82 female) were included in the present prospective study, of whom 21 died. Univariate and multivariate logistic regression analysis revealed that age ≥65 years (OR 3.765, 95% CI 1.146‒17.394; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 0.755‒8.044; p=0.007), CD3+CD8+ T-cells ≤75 cells·μL−1 (OR 3.982, 95% CI 1.132‒14.006; p We identified four risk factors: age ≥65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3+CD8+ T-cells ≤75 cells·μL−1 and cardiac troponin I ≥0.05 ng·mL−1. The latter two factors, especially, were predictors for mortality of COVID-19 pneumonia patients.read more
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Bacterial Pneumonia Co-Infection in COVID-19 Patients
Abdul Karim Othman,Mohd Nazri Ali,Nurul Ilani Bahar,Nurul Aimi Mustaffa,Wan Nasrudin Wan Ismail,Mazelan Omar,Intan Suhana Munira Mat Azmi +6 more
TL;DR: This study reported two cases of elderly patients with multiple comorbidities infected with SARS-Cov-2 and developed COVID-19 bacterial pneumonia requiring admission to intensive care unit (ICU) with one mortality preceded by septicemic shock and multi-organ failures.
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Survival Time, Mortality Rate, and Predicted Deaths for COVID-19 In-Patients in the United Kingdom
Christopher Hillyar,Anjan Nibber +1 more
TL;DR: The mortality rate of COVID-19 in-patients is approximately one fifth, leading to 33,730 additional deaths by 30 Apr 2020, and future research is required to confirm these estimates in specific subgroups of CO VID-19 patients.
Journal ArticleDOI
Clinical course and outcomes of COVID-19 patients with a history of cerebrovascular disease: a retrospective study in Wuhan
Yang Bai,Yong Liang,Fang Wang,Ligang Chen,Yulong Zhao,Shoujie Zhao,Yejing Zhu,Yushu Dong,Guobiao Liang,Dongfeng Chen,Lei Liu,Lei Liu +11 more
TL;DR: In this paper, a single-center retrospective study was performed at Huoshenshan Hospital in Wuhan, China, where patients with confirmed COVID-19 who had pre-existing cerebrovascular disease (CVD) were identified.
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Acute limb ischemia in patients with COVID-19
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Impact of a telemedicine system on work burden and mental health of healthcare providers working with COVID-19: a multicenter pre-post prospective study
Nobuyuki Kagiyama,Takayuki Komatsu,Masanori Nishikawa,Makoto Hiki,Mariko Kobayashi,W Matsuzawa,Hiroyuki Daida,Tohru Minamino,Toshio Naito,Manabu Sugita,Kunihisa Miyazaki,Hideaki Anan,Takatoshi Kasai +12 more
TL;DR: Investigating whether a telemedicine system reduces physical contact in addressing the COVID-19 pandemic and mitigates nurses’ distress and depression finds that the system is easy and effective in reducing healthcare providers’ infection risk.
References
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Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
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TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
Journal ArticleDOI
Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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