Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2: a prospective cohort study.
Rong Hui Du,Li Rong Liang,Cheng Qing Yang,Wen Wang,Tan Ze Cao,Ming Li,Guang Yun Guo,Juan Du,Chun Lan Zheng,Qi Zhu,Ming Hu,Xu Yan Li,Peng Peng,Huan-Zhong Shi +13 more
TLDR
Age ≥65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3+CD8+ T-cells ≤75 cells·μL−1 and cardiac troponin I ≥0.05 ng·mL−1 were four risk factors predicting high mortality of COVID-19 pneumonia patients.Abstract:
The aim of this study was to identify factors associated with the death of patients with COVID-19 pneumonia caused by the novel coronavirus SARS-CoV-2. All clinical and laboratory parameters were collected prospectively from a cohort of patients with COVID-19 pneumonia who were hospitalised to Wuhan Pulmonary Hospital (Wuhan City, Hubei Province, China) between 25 December 2019 and 7 February 2020. Univariate and multivariate logistic regression was performed to investigate the relationship between each variable and the risk of death of COVID-19 pneumonia patients. In total, 179 patients with COVID-19 pneumonia (97 male and 82 female) were included in the present prospective study, of whom 21 died. Univariate and multivariate logistic regression analysis revealed that age ≥65 years (OR 3.765, 95% CI 1.146‒17.394; p=0.023), pre-existing concurrent cardiovascular or cerebrovascular diseases (OR 2.464, 95% CI 0.755‒8.044; p=0.007), CD3+CD8+ T-cells ≤75 cells·μL−1 (OR 3.982, 95% CI 1.132‒14.006; p We identified four risk factors: age ≥65 years, pre-existing concurrent cardiovascular or cerebrovascular diseases, CD3+CD8+ T-cells ≤75 cells·μL−1 and cardiac troponin I ≥0.05 ng·mL−1. The latter two factors, especially, were predictors for mortality of COVID-19 pneumonia patients.read more
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The Association of Low CD4 Expression on Monocytes and Low CD8+ T-Cell Count at Hospital Admission Predicts the Need for Mechanical Ventilation in Patients With COVID-19 Pneumonia: A Prospective Monocentric Cohort Study
Jérôme Allardet-Servent,Inès Ait Belkacem,Tewfik Miloud,L Benarous,Franck Galland,Philippe Halfon,Jean-Louis Mege,Guillaume Penaranda,Jean-Marc Busnel,Fabrice Malergue +9 more
TL;DR: In this article , the authors identify COVID-19-associated immunophenotyping patterns at hospital admission and determine if some patterns could predict the need for mechanical ventilation (MV).
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FACTORS AFFECTING INTENSIVE CARE AND MORTALITY IN SARS-CoV 2019 HOSPITAL PATIENTS
TL;DR: Hydxychloroquine, favipravir, methylprednisolone and enoxoparin are effective in reducing mortality in the treatment and will be important in predicting prognosis and mortality and in effective patient management.
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Do the Clinical Management Guidelines for Covid-19 in African Countries Reflect the African Quality Palliative Care Standards? A Review of Current Guidelines.
Oladayo A Afolabi,Oladayo A Afolabi,Mary Abboah-Offei,Eve Namisango,Eve Namisango,Emeka Chukwusa,Adejoke O Oluyase,Emmanuel Luyirika,Richard Harding,Kennedy Nkhoma +9 more
TL;DR: In this article, the palliative care recommendations within COVID-19 case management guidelines in African countries were identified and critically appraised using African Palliative Care Association standards.
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Hospitalized COVID-19 Patients with Severe Acute Respiratory Syndrome: A Population-Based Registry Analysis to Assess Clinical Findings, Pharmacological Treatment and Survival
Eduardo Gutiérrez-Abejón,Francisco Herrera-Gómez,M. A. Pedrosa-Naudín,Eduardo Tamayo,Francisco Javier Álvarez +4 more
TL;DR: Patients older than 65 years who develop DIC have a higher probability of hospital death, and Tocilizumab and steroids have been linked to a lower incidence ofhospital death, being the main treatment for COVID-19 hospitalized patients with SARS.
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Infección por SARS-CoV-2 y seroprevalencia en pacientes con esclerosis múltiple
TL;DR: In this article, the efecto de infeccion por SARS-CoV-2 in los pacientes con esclerosis multiple (EM) and the influencia of los tratamientos modificadores de la enfermedad (TME) is desconocida.
References
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TL;DR: The epidemiological and clinical characteristics of novel coronavirus (2019-nCoV)-infected pneumonia in Wuhan, China, and hospital-associated transmission as the presumed mechanism of infection for affected health professionals and hospitalized patients are described.
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Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study
Nanshan Chen,Min Zhou,Xuan Dong,Jie-Ming Qu,Fengyun Gong,Yang Han,Yang Qiu,Jingli Wang,Ying Liu,Yuan Wei,Jia'an Xia,Ting Yu,Xinxin Zhang,Li Zhang +13 more
TL;DR: Characteristics of patients who died were in line with the MuLBSTA score, an early warning model for predicting mortality in viral pneumonia, and further investigation is needed to explore the applicability of the Mu LBSTA scores in predicting the risk of mortality in 2019-nCoV infection.
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