Proteins involved in mitochondrial metabolic functions and fertilization predominate in stallions with better motility.
Gemma Gaitskell-Phillips,Francisco E. Martín-Cano,José M. Ortiz-Rodríguez,Antonio Silva-Rodríguez,Eva da Silva-Álvarez,Patricia Rojo-Domínguez,Jose A. Tapia,María Concepción Robles Gil,Cristina Ortega-Ferrusola,Fernando J. Peña +9 more
TLDR
In this paper, the authors investigate differences among stallions of variable sperm quality (based on motility and sperm velocities), although all horses had sperm characteristics within normal ranges.About:
This article is published in Journal of Proteomics.The article was published on 2021-07-21 and is currently open access. It has received 4 citations till now. The article focuses on the topics: Sperm motility & Sperm.read more
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The stallion spermatozoa: A valuable model to help understand the interplay between metabolism and redox (de)regulation in sperm cells.
Fernando J. Peña,Cristian O'Flaherty,José M. Ortiz-Rodríguez,Francisco Eduardo Martín Cano,Gemma Gaitskell-Phillips,Maria Cruz Gil,Cristina Ortega-Ferrusola +6 more
TL;DR: Increasing knowledge on sperm metabolism and its interactions with redox regulation, may improve current sperm technologies in use and shall provide new clues to the understanding of male factor infertility.
Journal ArticleDOI
The challenge to produce magnetic nanoparticles from waste containing heavy metals aiming at biomedical application: New horizons of chemical recycling
TL;DR: Silica-coated magnetite nanoparticles (SMNPs) were prepared by a green approach based on waste pickling acid as mentioned in this paper , and a set of techniques were used for their characterization, and for monitoring the levels of heavy metal impurities.
Journal ArticleDOI
TMT-based comparative proteomic analysis of Dezhou donkey spermatozoa related to freezability.
Jie Yu,Haibing Liu,Xuexian Li,Shihao Ge,Xianlin Zhao,Chuan-Liang Ji,Yantao Wang,Zhaofei Wang,Ruihua Dang,Fuwei Zhao +9 more
TL;DR: In this paper , the authors used Tandem Mass Tag (TMT) peptide labeling coupled with LC-MS/MS approach to identify the different abundance sperm proteins in good freezability ejaculates (GFEs) and poor freezable ejaculate (PFEs), and found that upregulated proteins in GF group were mainly involved in N-Glycan biosynthesis and protein processing in endoplasmic reticulum.
Journal ArticleDOI
Dataset of the sperm proteome of stallions with different motility
Gemma Gaitskell-Phillips,Francisco E. Martín-Cano,J. M. Ortiz-Rodriguez,Antonio Silva Rodríguez,E. Da Silva-Álvarez,Maria Cruz Gil,Cristina Ortega-Ferrusola,Fernando J. Peña +7 more
TL;DR: A detailed set of data on how the stallion sperm proteome differs among stallions with different sperm motilities, although within normal ranges, was provided in this article , which can be used to disclose potential targets to identify good sperm samples and to study specific pathways involved in the regulation of sperm motility.
References
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PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database
TL;DR: PathwayVoyager represents an alternative approach to many already existing, more complex pathway reconstructions software solutions and is ideally suited for environments where analyses on variable datasets are desired.
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KEGG-PATH: Kyoto encyclopedia of genes and genomes-based pathway analysis using a path analysis model
TL;DR: A path analysis model (KEGG-PATH) is developed to subdivide the total effect of each K EGG pathway into the direct effect and indirect effect by taking into account not only each KEGG pathway itself, but also the correlation with its related pathways.
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Mitochondrial Bound Hexokinase Activity as a Preventive Antioxidant Defense STEADY-STATE ADP FORMATION AS A REGULATORY MECHANISM OF MEMBRANE POTENTIAL AND REACTIVE OXYGEN SPECIES GENERATION IN MITOCHONDRIA
Wagner Seixas da-Silva,Armando Gómez-Puyou,Marietta Tuena de Gómez-Puyou,Rafael Moreno-Sánchez,Fernanda G. De Felice,Leopoldo de Meis,Marcus F. Oliveira,Antonio Galina +7 more
TL;DR: It is shown that the ADP produced by hexokinase activity in rat brain mitochondria (mt-hexokinase) controls both membrane potential (Δψm) and ROS generation and mitochondrial ROS generation through an ADP-recycling mechanism.
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The Paradoxical Relationship Between Stallion Fertility and Oxidative Stress
TL;DR: The equine is the first mammal in which such a positive relationship between oxidative stress and functionality has been observed, with implications for the management of stallion fertility in vitro and in vivo.
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Detection of "apoptosis-like" changes during the cryopreservation process in equine sperm.
Cristina Ortega-Ferrusola,Y Sotillo-Galán,E Varela-Fernández,J.M. Gallardo-Bolaños,A. Muriel,Lauro González-Fernández,Jose A. Tapia,Fernando J. Peña +7 more
TL;DR: It is proposed that sperm mitochondria may be directly involved in the subtle damage that is present in most spermatozoa surviving freezing and thawing.