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Open AccessJournal ArticleDOI

Proteinuria and the risk of developing end-stage renal disease

TLDR
Proteinuria was a strong, independent predictor of ESRD in a mass screening setting in Okinawa, Japan, and therefore, asymptomatic proteinuria warrants further work-up and intervention.
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This article is published in Kidney International.The article was published on 2003-04-01 and is currently open access. It has received 507 citations till now. The article focuses on the topics: End stage renal disease & Mass screening.

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Chronic kidney disease: the global challenge

TL;DR: The epidemiology of CKD worldwide, with emphasis on early detection and prevention, and the feasibility of methods for detection and primary prevention is examined, and strategic recommendations based on future research to stem the worldwide growth of CKd are made.
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Lower estimated GFR and higher albuminuria are associated with adverse kidney outcomes. A collaborative meta-analysis of general and high-risk population cohorts

TL;DR: Lower eGFR and higher albuminuria are risk factors for ESRD, acute kidney injury and progressive CKD in both general and high-risk populations, independent of each other and of cardiovascular risk factors.
References
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Journal ArticleDOI

The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The collaborative study group

TL;DR: Captopril protects against deterioration in renal function in insulin-dependent diabetic nephropathy and is significantly more effective than blood-pressure control alone.
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The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy.

TL;DR: Whether captopril has kidney-protecting properties independent of its effect on blood pressure in diabetic nephropathy is determined.
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Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency

TL;DR: A study to determine the effect of the angiotensin-converting–enzyme inhibitor benazepril on the progression of renal insufficiency in patients with various underlying renal diseases.
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Hyperhomocysteinemia in end-stage renal disease: Prevalence, etiology, and potential relationship to arteriosclerotic outcomes

TL;DR: This review will first place hyperhomocysteinemia in the context of the other established amino acid abnormalities characteristic of ESRD, followed by discussions of the epidcmiological and experimental evidence linking hyper-
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