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羟氨苄青霉素引起大疱性类天疱疮样疹
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This article is published in International Journal of Dermatology and Venereology.The article was published on 1992-11-15 and is currently open access. It has received 2147 citations till now.read more
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Conformationally restricted analogs of oxytocin; stabilization of inhibitory conformation.
M. Lebl,M. Lebl,Patricia S. Hill,Wieslaw M. Kazmierski,Lenka Kárászová,Jiřina Slaninová,Ivo Frič,Victor J. Hruby +7 more
TL;DR: 1H NMR and CD studies suggest that the conformational properties of the analog containing D-tetrahydroisoquinoline carboxylic acid are similar to those of [2-D-phenylalanine]oxytocin.
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Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.
Shaun Martin,Sarah van Veen,Tine Holemans,Seyma Demirsoy,Chris Van den Haute,Veerle Baekelandt,Patrizia Agostinis,Jan Eggermont,Peter Vangheluwe +8 more
TL;DR: It is demonstrated that PA and PI(3,5)P2 are also required for the ATP13A2-mediated protection against the toxic metals Mn2+, Zn2+, and Fe3+, suggesting a general lipid-dependent activation mechanism of ATP13a2 in various PD-related stress conditions.
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Early stratigraphic record and phylogeny of the planktonic genus Guembelitria Cushman, 1933
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Life Cycle Thinking in Impact Assessment: current practice and LCA gains
TL;DR: In this paper, a review of 85 Danish impact assessment reports was carried out, which were analyzed for analytical appropriateness and application of LCT in the context of impact assessment, and the results revealed that LCT is appropriate for most of the IAs, but rarely applied to provide such a perspective.
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Transient receptor potential: a large family of new channels of which several are involved in cardiac arrhythmia.
Guy Vassort,Julio Alvarez +1 more
TL;DR: Several neurotransmitters that activate the formation of diacylglycerol could modulate cardiac rhythm or, like ATP, induce arrhythmia.
References
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Biological roles of oligosaccharides: all of the theories are correct
TL;DR: The only common features of the varied functions of oligosaccharides are that they either mediate ‘specific recognition’ events or that they provide ‘modulation’ of biological processes.
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Meta-analysis of risk factors for posttraumatic stress disorder in trauma-exposed adults.
TL;DR: The effect size of all the risk factors was modest, but factors operating during or after the trauma, such as trauma severity, lack of social support, and additional life stress, had somewhat stronger effects than pretrauma factors.
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Bibliometric Methods in Management and Organization
Ivan Zupic,Tomaž Čater +1 more
TL;DR: It is envisioned that bibliometric methods will complement meta-analysis and qualitative structured literature reviews as a method for reviewing and evaluating scientific literature and hold the potential to increase rigor and mitigate researcher bias in reviews of scientific literature.
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A global boom in hydropower dam construction
Christiane Zarfl,Christiane Zarfl,Alexander E. Lumsdon,Alexander E. Lumsdon,Jürgen Berlekamp,Laura Tydecks,Klement Tockner,Klement Tockner +7 more
TL;DR: In this article, major new initiatives in hydropower development are now under way, and at least 3,700 major dams, each with a capacity of more than 1MW, are either planned or under construction, primarily in countries with emerging economies.
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A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy
Rando Allikmets,Nanda A. Singh,Hui Sun,Noah F. Shroyer,Amy Hutchinson,Abirami Chidambaram,Bernard Gerrard,Lisa Baird,Dora Stauffer,Andy Peiffer,Amir Rattner,Philip M. Smallwood,Yixin Li,Kent L. Anderson,Richard A. Lewis,Jeremy Nathans,Mark Leppert,Michael Dean,James R. Lupski +18 more
TL;DR: Mutational analysis of ABCR in STGD families revealed a total of 19 different mutations including homozygous mutations in two families with consanguineous parentage, indicating that ABCR is the causal gene of STGD/FFM.