Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins
TLDR
In a system containing a suspension of red blood cells in a mixed solution of high density lipoproteins (HDL) and LDL, the fractional rate of exchange of HDL cholesterol was most rapid followed by LDL and lastly, by red cells.About:
This article is published in Journal of Lipid Research.The article was published on 1970-11-01 and is currently open access. It has received 102 citations till now. The article focuses on the topics: Intermediate-density lipoprotein & Cholesterol.read more
Citations
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The role of lipoproteins in steroidogenesis and cholesterol metabolism in steroidogenic glands.
John T. Gwynne,Jerome F. Strauss +1 more
TL;DR: Two distinct lipoprotein-specific, hormonally regulated mechanisms for Lipoprotein cholesterol uptake by steroidogenic tissues have been elucidated.
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Mechanisms and consequences of cellular cholesterol exchange and transfer
TL;DR: The influence of enzymes such as lecithin-cholesterol acyltransferase and hepatic lipase on the direction of net transfer of free cholesterol between lipoproteins and cells can be understood in terms of their effects on the pool sizes and the rate constants for influx and efflux.
Journal ArticleDOI
A molecular membrane model of sperm capacitation and the acrosome reaction of mammalian spermatozoa
TL;DR: The model illustrates enzymatic reactions which are believed to regulate the permeability and integrity of the plasma membrane overlying the acrosome during interactions between the male gamete and capacitation factors present in fluids of the female genital tract.
Journal ArticleDOI
Mechanism of cholesterol and phosphatidylcholine exchange or transfer between unilamellar vesicles
L R McLean,M C Phillips +1 more
TL;DR: Results are only consistent with a mechanism of lipid exchange in which cholesterol and phosphatidylcholine diffuse through the aqueous phase; the experimental activation energy is associated with desorption of lipid from the donor bilayer into the aaqueous phase.
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Phosphatidylethanolamine Is a Key Regulator of Membrane Fluidity in Eukaryotic Cells
Rosie Dawaliby,Cataldo Trubbia,Cédric Delporte,Caroline Noyon,Jean Marie Ruysschaert,Pierre Van Antwerpen,Cédric Govaerts +6 more
TL;DR: It is shown here that insect and mammalian cells present similar microviscosity at their respective physiological temperature, indicating that both cell types combine regulation by sterols and phospholipids to control proper membrane fluidity.
References
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A simplified method for the estimation of total cholesterol in serum and demonstration of its specificity.
TL;DR: The simplified but precise method described in this paper involves treatment of the serum with alcoholic potassium hydroxide to liberate the cholesterol from the lipoprotein complexes and to saponify the cholesterol esters.
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Improved procedure for the extraction of lipids from human erythrocytes.
Herbert G. Rose,Morris Oklander +1 more
TL;DR: In this article, a procedure for the extraction of human erythrocyte lipids using chloroform-isopropanol 7:11 (v/v) was described.
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[On a rapid determination of the cholesterol bound to the serum alpha- and beta-lipoproteins].
M. Burstein,Samaille J +1 more
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The Routine Fitting of Kinetic Data to Models: A Mathematical Formalism for Digital Computers
TL;DR: In this article, a mathematical formalism is presented for use with digital computers to permit the routine fitting of data to physical and mathematical models, given a set of data, the mathematical equations describing a model, initial conditions for an experiment, and initial estimates for the values of model parameters.
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Turnover of plasma cholesterol in man
TL;DR: Analysis of the turnover curves of plasma cholesterol revealed that in every study the turnover of cholesterol conformed to a two-pool model, and cholestyramine therapy produced a large increase in PR(A) and in the rate of removal from pool A.
Related Papers (5)
The in vitro interchange of cholesterol between plasma and red cells.
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