Journal ArticleDOI
Recent advances in molecular imprinting technology: current status, challenges and highlighted applications
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This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs.Abstract:
Molecular imprinting technology (MIT) concerns formation of selective sites in a polymer matrix with the memory of a template. Recently, molecularly imprinted polymers (MIPs) have aroused extensive attention and been widely applied in many fields, such as solid-phase extraction, chemical sensors and artificial antibodies owing to their desired selectivity, physical robustness, thermal stability, as well as low cost and easy preparation. With the rapid development of MIT as a research hotspot, it faces a number of challenges, involving biological macromolecule imprinting, heterogeneous binding sites, template leakage, incompatibility with aqueous media, low binding capacity and slow mass transfer, which restricts its applications in various aspects. This critical review briefly reviews the current status of MIT, particular emphasis on significant progresses of novel imprinting methods, some challenges and effective strategies for MIT, and highlighted applications of MIPs. Finally, some significant attempts in further developing MIT are also proposed (236 references).read more
Citations
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Journal ArticleDOI
Molecular imprinting: perspectives and applications
TL;DR: This work proposes to comprehensively review the recent advances in molecular imprinting including versatile perspectives and applications, concerning novel preparation technologies and strategies of MIT, and highlight the applications of MIPs.
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Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
TL;DR: This review systematically introduces the classification, catalytic mechanism, activity regulation as well as recent research progress of nanozymes in the field of biosensing, environmental protection, and disease treatments, etc. in the past years.
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Biological and chemical sensors based on graphene materials
TL;DR: This article critically and comprehensively reviews the emerging graphene-based electrochemical sensors, electronic sensors, optical sensors, and nanopore sensors for biological or chemical detection and emphasizes on the underlying detection (or signal transduction) mechanisms.
Journal ArticleDOI
Molecular Imprinting on Inorganic Nanozymes for Hundred-fold Enzyme Specificity
TL;DR: Molecular imprinting furthers the functional enzyme mimicking aspect of nanozymes, and such hybrid materials will find applications in biosensor development, separation, environmental remediation, and drug delivery.
Journal ArticleDOI
Molecular imprinting science and technology: a survey of the literature for the years 2004-2011.
TL;DR: A survey of the literature covering the development of molecular imprinting science and technology over the years 2004–2011 and efforts to apply these polymeric materials to a range of application areas is presented.
References
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Journal ArticleDOI
Molecular Imprinting in Cross‐Linked Materials with the Aid of Molecular Templates— A Way towards Artificial Antibodies
TL;DR: In this article, the authors present a method analogous to a mechanism of antibody formation proposed earlier, by which in the presence of interacting monomers a cross-linked polymer is formed around a molecule that acts as a template.
Journal ArticleDOI
Molecular imprinting science and technology: a survey of the literature for the years up to and including 2003
Cameron Alexander,Håkan S. Andersson,Lars I. Andersson,Richard J. Ansell,Nicole Kirsch,Ian A. Nicholls,John O’Mahony,Michael J. Whitcombe +7 more
TL;DR: In the presentation of the assembled references, a section presenting reviews and monographs covering the area is followed by papers dealing with fundamental aspects of molecular imprinting and the development of novel polymer formats.
Journal ArticleDOI
A new method for the introduction of recognition site functionality into polymers prepared by molecular imprinting : synthesis and characterization of polymeric receptors for cholesterol
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Molecularly imprinted polymers : man-made mimics of antibodies and their applications in analytical chemistry
TL;DR: An overview of the development of molecular imprinting can be found in this paper, where the authors present a survey of the history of molecular polymer formulations and their application in the field of ligand recognition.
Journal ArticleDOI
A surface functional monomer-directing strategy for highly dense imprinting of TNT at surface of silica nanoparticles.
TL;DR: A critical value of shell thickness for the maximum rebindingcapacity was determined by testing the evolution of rebinding capacity with shell thickness, which provides new insights into the effectiveness of molecular imprinting and the form of imprinted materials.
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