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Open AccessJournal ArticleDOI

Results of a worldwide survey on the assessment of platelet function by light transmission aggregometry: a report from the platelet physiology subcommittee of the SSC of the ISTH.

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TLDR
A large, detailed, global survey of light transmission aggregometry practices shows a very high variability in LTA practices worldwide, and, as a consequence, methodological standardization is necessary.
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This article is published in Journal of Thrombosis and Haemostasis.The article was published on 2009-06-01 and is currently open access. It has received 192 citations till now. The article focuses on the topics: Platelet disorder & Sample collection.

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Journal ArticleDOI

Recommendations for the standardization of light transmission aggregometry : a consensus of the working party from the platelet physiology subcommittee of SSC/ISTH

TL;DR: The Platelet Physiology Subcommittee of the Scientific and Standardization Committee (SSC) of the International Society on Thrombosis and Haemostasis formed a working party of experts with the aim of producing a series of consensus recommendations for standardizing LTA, which formed the basis of a consensus document, which is the subject of the present report.
Journal ArticleDOI

Guidelines for the laboratory investigation of heritable disorders of platelet function.

TL;DR: The objective of this guideline is to provide healthcare professionals with clear guidance on platelet function testing in patients with suspected bleeding disorders and in all cases individual patient circumstances may dictate an alternative approach.
Journal ArticleDOI

In the presence of strong P2Y12 receptor blockade, aspirin provides little additional inhibition of platelet aggregation.

TL;DR: P2Y12 receptor blockade alone causes inhibition of platelet aggregation that is little enhanced by aspirin, and the antiaggregatory effects of PAM were associated with reductions in the platelet release of both TXA2 and ATP + ADP.
Journal ArticleDOI

Development of North American consensus guidelines for medical laboratories that perform and interpret platelet function testing using light transmission aggregometry.

TL;DR: In this paper, the authors developed guidelines for platelet function testing by consensus for expert recommendations that included recommendations on the evaluation and interpretation of light transmission platelet aggregometry (LTA), which is important for the diagnostic evaluation of common and rare bleeding disorders.
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